Journal ArticleDOI
Standardisation of platelet counting accuracy in blood banks by reference to an automated immunoplatelet procedure: comparative evaluation of Cell-Dyn CD4000 impedance and optical platelet counts
TLDR
The use in this study of a standardised immunoplatelet reference method to examine the question of analyser suitability for determining platelet counts/yields of platelet units thus provided a number of important findings.About:
This article is published in Transfusion and Apheresis Science.The article was published on 2001-10-01. It has received 15 citations till now. The article focuses on the topics: Population.read more
Citations
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Journal ArticleDOI
Clinical effect of buffy-coat vs. apheresis platelet concentrates in patients with severe thrombocytopenia after intensive chemotherapy.
Ciǧdem Akalin Akkök,L. Brinch,G. F. Lauritzsen,Bjarte G. Solheim,Jens Kjeldsen-Kragh,Jens Kjeldsen-Kragh +5 more
TL;DR: This prospective observational study compared apheresis PCs harvested by Amicus cell separator with buffy‐coat PCs during storage for up to 6·5 days with improved PC quality after introduction of storage containers that are more oxygen permeable than the second‐generation PC containers.
Journal ArticleDOI
Accuracy of platelet counting by automated hematologic analyzers in acute leukemia and disseminated intravascular coagulation: potential effects of platelet activation.
TL;DR: It is interesting that platelet activation markers were associated with DIC severity and erroneous platelet counting, suggesting that platelets activation is a potential source of inaccuracy.
Journal ArticleDOI
The platelet count accuracy of platelet concentrates obtained by using automated analysis is influenced by instrument bias and activated platelet components.
TL;DR: This data indicates that the blood platelet content (in numbers) of platelet concentrates is required for production quality control and to predict clinical responses.
Journal ArticleDOI
Caracterização, produção e indicação clínica dos principais hemocomponentes
TL;DR: The authors revisar os procedimentos de coleta, producao, armazenamento, and a indicacao clinica dos principal hemocomponentes, como concentrado de hemacias, concentrada de hemaceres, lavadas, eritrocitos pobres em leucocitos, concentratedrado of plaquetas, concentrabado de plasquetas por aferese, concentradado de granulocito, plasma fresco congelado, plasma normal o
Journal ArticleDOI
In vitro evaluation of platelet concentrates during storage: Platelet counts and markers of platelet destruction
TL;DR: Investigation of single-donor platelet concentrates found increasing impedance-immunoplatelet ratio was observed during storage, correlating to platelet fragments, large platelets, platelet density and cell-lysis, and optical platelet count is not recommended.
References
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Journal ArticleDOI
Statistical methods for assessing agreement between two methods of clinical measurement.
TL;DR: An alternative approach, based on graphical techniques and simple calculations, is described, together with the relation between this analysis and the assessment of repeatability.
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Guide to the Preparation, Use and Quality Assurance of Blood Components
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Safety and Cost Effectiveness of a 10 × 109/L Trigger for Prophylactic Platelet Transfusions Compared With the Traditional 20 × 109/L Trigger: A Prospective Comparative Trial in 105 Patients With Acute Myeloid Leukemia
Hannes Wandt,Markus Frank,Gerhard Ehninger,Christiane Schneider,Norbert Brack,Ali Daoud,Irene Fackler-Schwalbe,Jürgen Fischer,Ringfried Gäckle,Thomas Geer,Peter Harms,Birgit Löffler,Siegfried Öhl,Burkhard Otremba,Monika Raab,Petra Schönrock-Nabulsi,Gerhard Strobel,Rolf Winter,Hartmut Link +18 more
TL;DR: The cost of platelet therapy is one third lower in group A compared with group B without any associated increase in bleeding risk, and there were no significant differences in the number of red blood cell transfusions administered between the two groups.
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Randomized study of prophylactic platelet transfusion threshold during induction therapy for adult acute leukemia: 10,000/microL versus 20,000/microL.
TL;DR: Giving prophylactic platelets at a threshold of < or = 10,000/microL compared with < or means 20,000 /microL can decrease the total utilization of platelets with only a small adverse effect on bleeding, and no statistically significant effect on morbidity.
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Platelet activation during preparation of platelet concentrates: a comparison of the platelet-rich plasma and the buffy coat methods.
R. Fijnheer,Ruby N.I. Pietersz,Dirk de Korte,C. W. N. Gouwerok,W.J.A. Dekker,H. W. Reesink,Dirk Roos +6 more
TL;DR: It was concluded that, immediately after preparation, PRP‐derived platelets are more activated than BC‐ derived platelets, most likely a result of the pelleting that follows the second high‐speed centrifugation of the PRP.