Journal ArticleDOI
State-of-the-art retinal optical coherence tomography
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TLDR
Extensions of OCT have been developed to enhance image contrast and to enable non-invasive depth-resolved functional imaging of the retina, thus providing blood flow, spectroscopic, polarization-sensitive and physiological information.About:
This article is published in Progress in Retinal and Eye Research.The article was published on 2008-01-01. It has received 793 citations till now. The article focuses on the topics: Optical coherence tomography & Optical Biopsy.read more
Citations
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Journal ArticleDOI
Going deeper than microscopy: the optical imaging frontier in biology
TL;DR: This Review discusses promising photonic methods that have the ability to visualize cellular and subcellular components in tissues across different penetration scales, according to the tissue depth at which they operate.
Journal Article
Optical Coherence Tomography of the Human Retina
Michael R. Hee,Joseph A. Izatt,Eric A. Swanson,David Huang,Joel S. Schuman,Charles P. Lin,Carmen A. Puliafito,James G. Fujimoto +7 more
TL;DR: In this article, optical coherence tomography is used for high-resolution, noninvasive imaging of the human retina, including the macula and optic nerve head in normal human subjects.
Journal Article
Measurement of intraocular distances by backscattering spectral interferometry
TL;DR: In this article, the diffraction tomography theorem is adapted to one-dimensional length measurement and the resulting spectral interferometry technique is described and the first length measurements using this technique on a model eye and on a human eye in vivo are presented.
Journal ArticleDOI
Optical coherence tomography angiography: A comprehensive review of current methods and clinical applications.
Amir H. Kashani,Chieh-Li Chen,Jin Kyu Gahm,Fang Zheng,Grace M. Richter,Philip J. Rosenfeld,Yonggang Shi,Ruikang K. Wang +7 more
TL;DR: The methods used to create OCTA images, the practical applications of OCTA in light of invasive dye‐imaging studies (e.g. fluorescein angiography) and clinical studies demonstrating the utility of OCT a for research and clinical practice are discussed.
Journal ArticleDOI
Automated 3-D Intraretinal Layer Segmentation of Macular Spectral-Domain Optical Coherence Tomography Images
Mona K. Garvin,Michael D. Abràmoff,Xiaodong Wu,Stephen R. Russell,Trudy L. Burns,Milan Sonka +5 more
TL;DR: A graph-theoretic segmentation method for the simultaneous segmentation of multiple 3-D surfaces that is guaranteed to be optimal with respect to the cost function and that is directly applicable to the segmentations of 3- D spectral OCT image data is reported.
References
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Journal ArticleDOI
Optical coherence tomography
David Huang,Eric A. Swanson,Charles P. Lin,Joel S. Schuman,William G. Stinson,Warren Chang,Michael R. Hee,Thomas J. Flotte,Kenton W. Gregory,Carmen A. Puliafito,James G. Fujimoto +10 more
TL;DR: OCT as discussed by the authors uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way analogous to ultrasonic pulse-echo imaging.
Book ChapterDOI
Optical Coherence Tomography
Eric A. Swanson,J. Izatt,M. Bee,David Huang,Charles P. Lin,Carmen A. Puliafito,Carmen A. Puliafito,James G. Fujimoto +7 more
TL;DR: Optical coherence tomography (OCT) has developed rapidly since its first realisation in medicine and is currently an emerging technology in the diagnosis of skin disease as mentioned in this paper, where OCT is an interferometric technique that detects reflected and backscattered light from tissue.
Journal ArticleDOI
Sensitivity advantage of swept source and Fourier domain optical coherence tomography
TL;DR: Results are presented which demonstrate the superior sensitivity of swept source (SS) and Fourier domain (FD) optical coherence tomography (OCT) techniques over the conventional time domain (TD) approach.
Journal ArticleDOI
Performance of fourier domain vs. time domain optical coherence tomography.
TL;DR: It is shown that FDOCT systems have a large sensitivity advantage and allow for sensitivities well above 80dB, even in situations with low light levels and high speed detection.
Journal ArticleDOI
Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography
Johannes F. de Boer,Barry Cense,B. Hyle Park,Mark C. Pierce,Guillermo J. Tearney,Brett E. Bouma +5 more
TL;DR: A signal-to-noise ratio (SNR) analysis is presented for optical coherence tomography (OCT) signals in which time-domain performance is compared with that of the spectral domain.