Journal ArticleDOI
Sterol balance studies in the rat. Effects of dietary cholesterol and β-sitosterol on sterol balance and rate-limiting enzymes of sterol metabolism
Robert F. Raicht,Robert F. Raicht,Bertram I. Cohen,Bertram I. Cohen,Sarah Shefer,Sarah Shefer,Erwin H. Mosbach,Erwin H. Mosbach +7 more
TLDR
Measurements of the activities of the rate-limiting enzymes showed fair correlation with cholesterol-bile acid balance, and in beta-sitosterol-fed animals, the reductase was increased 2-fold and cholesterol 7 alpha-hydroxylase was not significantly different from controls.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1975-06-23. It has received 83 citations till now. The article focuses on the topics: Reverse cholesterol transport & Sterol.read more
Citations
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Journal ArticleDOI
Soy sterol esters and β-sitostanol ester as inhibitors of cholesterol absorption in human small bowel
TL;DR: Esterified soy sterols and beta-sitostanol inhibited cholesterol absorption equally, despite the different structures of the plant sterols.
Journal ArticleDOI
Plant sterol intakes and colorectal cancer risk in the Netherlands Cohort Study on Diet and Cancer.
TL;DR: A high dietary intake of plant sterols was not associated with a lower risk of colon and rectal cancers in the Netherlands Cohort Study on Diet and Cancer.
Book ChapterDOI
Chapter 9 Mechanism of bile acid biosynthesis in mammalian liver
TL;DR: This chapter discusses the mechanism of bile-acid biosynthesis in mammalian liver, and the conversion of cholesterol into bile acids represents the most obvious example of the high capacity of the liver to convert lipid- soluble material into excretable water-soluble products.
Journal ArticleDOI
Bile acid biosynthesis. Pathways and regulation.
E. H. Mosbach,Gerald Salen +1 more
TL;DR: This review summarizes certain biochemical aspects of bile acid biosynthesis that are defective in cerebrotendinous xanthomatosis (CTX), a rare, familial sterol storage disease.
References
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Journal ArticleDOI
The Biological Synthesis of Cholesterol
TL;DR: This chapter examines cholesterol metabolism in terms of the molecular events that are responsible for constructing cyclopentanoperhydrophenanthrene derivatives from small molecular precursors.
Journal ArticleDOI
Regulation of Cholesterol Metabolism
John M. Dietschy,Jean D. Wilson +1 more
TL;DR: The main source of cholesterol entering the miscible pools is dietary or exogenous cholesterol, and the essential features of the proce...
Journal ArticleDOI
Effects of dietary cholesterol on the regulation of total body cholesterol in man.
TL;DR: In the majority of cases the accumulation of cholesterol in body pools was small because of adequate compensation by reexcretion plus reduced synthesis, but in a few patients large accumulations occurred on high cholesterol diets when absorption exceeded the compensatory mechanisms.