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Stimulation of human peripheral lymphocytes by Zn2+ in vitro
H. Kirchner,H. Rühl +1 more
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This article is published in Experimental Cell Research.The article was published on 1970-07-01. It has received 88 citations till now. The article focuses on the topics: Stimulation.read more
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Zinc and the immune system
Lothar Rink,P Gabriel +1 more
TL;DR: The relationship between Zn and the immune system is complex, since there are four different types of influence associated with Zn: dietary intake and the resorption of Zn depends on the composition of the diet and also on age and disease status.
Journal ArticleDOI
Ion Channels in Innate and Adaptive Immunity
TL;DR: The mechanisms underlying the function of ion channels and transporters in lymphocytes and innate immune cells are reviewed and their roles in lymphocyte development, adaptive and innateimmune responses, and autoimmunity are discussed, as well as recent efforts to develop pharmacological inhibitors of ions for immunomodulatory therapy.
Zinc and immune system.
TL;DR: The relationship between Zn and the immune system is complex, since there are four different types of influence associated with Zn, which influence the function of immunostimulants used in the experimental systems and the therapeutic use of Zn will be discussed in detail.
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New aspects in the biological role of zinc: a stabilizer of macromolecules and biological membranes.
TL;DR: A personal and admittedly incomplete view of the latter aspect of the role of zinc in the stability of macromolecules, particularly the components of various biological membranes is presented.
Journal ArticleDOI
Ion channels and transporters in lymphocyte function and immunity
TL;DR: The roles of ion conduction pathways in lymphocyte function and immunity are discussed, which function as second messengers to regulate crucial lymphocyte effector functions, including cytokine production, differentiation and cytotoxicity.
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Journal ArticleDOI
The origin and kinetics of mononuclear phagocytes
Ralph van Furth,Zanvil A. Cohn +1 more
TL;DR: It was concluded that the rapidly dividing mononuclear phagocytes of the bone marrow, called promonocytes, are the progenitor cells of the monocytes and give rise to peritoneal macrophages.
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A zn++ requirement for synthesis of deoxyribonucleic acid by rat liver.
Motoji Fujioka,Irving Lieberman +1 more
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Zinc stimulation of rna and protein synthesis in rhizopus nigricans.
TL;DR: Analysis of cells during the course of growth, after addition of the metal, showed that there was an immediate increase in RNA, followed by a corresponding increase in protein and cell mass, and the DNA content was affected to a lesser extent.
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[Lymphocyte transformation in mercury hypersensitivity. Non-specific transformation due to mercury compounds].
TL;DR: Untersuchungen uber die in vitro-Transformation von Lymphocyten bei Fallen von Quecksilber-Kontaktallergic fuhrten zu folgenden Ergebnissen: 1.
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Zur Wirkung von Zn2⊕ auf die nucleare RNA- und Proteinbiosynthese der Rattenleber / Effect of Zn2⊕ on Nuclear RNA- and Protein-Biosynthesis in Rat Liver
TL;DR: In this paper, female rats have been employed for a study of the reactivity of zinc ions on RNA and protein biosynthesis of liver nuclei, and they have been found to stimulate RNA biosynthesis up to 80% and a 40% increase of protein synthesis was observed under the same conditions.