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Open AccessJournal ArticleDOI

Strategy of prevention: lessons from cardiovascular disease.

Geoffrey Rose
- 06 Jun 1981 - 
- Vol. 282, Iss: 6279, pp 1847-1851
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TLDR
In this article, two types of preventive measures are proposed; the first consists in the removal of an unnatural factor and the restoration of biological normality as the reduction of intake of saturated fats would be in the case of heart disease; the second does not consist of removing a supposed cause of disease but in adding some other factors in the hope of conferring protection as a high intake of polyunsaturated fat and of long-term medication would be for heart disease.
Abstract
Prevention of coronary heart diseases seems to be possible as recent experiences in Australia and in the U.S. have shown. Increased risk of heart disease in women is presented by the use of hormonal contraceptives and in men by high cholesterol levels and by hypertension. Preventive strategy that concentrates on high-risk individuals has to consider the mass approach which however much it may offer to the community as a whole offers little to each participating individual; it is a measure which which applied to many will actually benefit few. There are 2 types of preventive measures; the first consists in the removal of an unnatural factor and the restoration of biological normality as the reduction of intake of saturated fats whould be in the case of heart disease; the second does not consist of removing a supposed cause of disease but in adding some other factors in the hope of conferring protection as a high intake of polyunsaturated fat and of long-term medication would be for heart disease. Preventive medicine can be helped by changes in behavior of society and such changes are often brought about not by medical measures but by social motivations and by the force of economics and convenience.

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References
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Journal ArticleDOI

A Co-operative trial in the primary prevention of ischaemic heart disease using clofibrate: Report1 from the Committee of Principal Investigators

TL;DR: A double-blind intervention trial to test the hypothesis that the incidence of ischaemic heart disease in middle-aged men can be reduced by lowering raised serum cholesterol levels found men with a substantial reduction of cholesterol concentration, who smoked, and also had above average blood pressure levels showed the most benefit.
Journal ArticleDOI

Smoking and other risk factors for coronary heart-disease in British civil servants.

TL;DR: A five-year follow-up of 18 403 male British civil servants between the age of 40 and 64, who had been the subject of an earlier clinical survey found 277 deaths from coronary heart-disease, confirmed that the main risk factors were independently related to cardiac morbidity and mortality.
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