Journal ArticleDOI
Strecker reaction and α-amino nitriles: Recent advances in their chemistry, synthesis, and biological properties
TLDR
In this article, a review of α-amino nitriles through the Strecker-type and α-cyanation reactions, their chemical and biological properties, as well as their synthetic application, paying attention on the wonderful capacity for generating novel molecular diversity for pharmacological, biological and agrochemical researches, which ends with the total synthesis of complex alkaloids, preparation of new N-heterocycles and αaminonitrile-containing drugs.About:
This article is published in Tetrahedron.The article was published on 2018-02-22. It has received 109 citations till now.read more
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Application of metal oxide semiconductors in light-driven organic transformations
Paola Riente Paiva,Timothy Noël +1 more
TL;DR: In this paper, the most relevant literature related to the use of metal oxide semiconductors as photocatalysts to light induce organic reactions, including oxidations, C-C and C-heteroatom bond formations.
Journal ArticleDOI
Synthesis of Nitriles from Primary Amides or Aldoximes under Conditions of a Catalytic Swern Oxidation
TL;DR: A diverse range of cyano compounds were obtained in good to excellent yields, including aromatic, heteroaromatic, cyclic, and acyclic aliphatic species.
Journal ArticleDOI
Sustainable Carbene Transfer Reactions with Iron and Light
Claire Empel,Rene M. Koenigs +1 more
TL;DR: In this paper, a metal-free carbene transfer reaction with visible light was demonstrated using diazoacetonitrile under photochemical conditions using visible light, which can open up new sustainable ways for the construction of small functional molecules.
Journal ArticleDOI
Straightforward α-Amino Nitrile Synthesis Through Mo(CO)6 -Catalyzed Reductive Functionalization of Carboxamides.
TL;DR: The methodology presented here, displays high levels of chemoselectivity allowing for the reduction of amides in the presence of functional groups such as ketones, imines, aldehydes, and acids, which affords a simple route for the synthesis of α-amino nitriles with a broad scope of functionalities in high yields.
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Photoinduced, Copper-Catalyzed Enantioconvergent Alkylations of Anilines by Racemic Tertiary Electrophiles: Synthesis and Mechanism.
TL;DR: In this article , a photoinduced enanti-convergent coupling of a variety of racemic tertiary alkyl electrophiles with aniline nucleophiles is reported.
References
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Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
TL;DR: The conversion of these bench stable, benign catalysts to redox-active species upon irradiation with simple household lightbulbs represents a remarkably chemoselective trigger to induce unique and valuable catalytic processes.
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Organic Photoredox Catalysis
TL;DR: An overview of the basic photophysics and electron transfer theory is presented in order to provide a comprehensive guide for employing this class of catalysts in photoredox manifolds.
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Solar Synthesis: Prospects in Visible Light Photocatalysis
TL;DR: A variety of reaction types have now been shown to be amenable to visible light photocatalysis via photoinduced electron transfer to or from the transition metal chromophore, as well as energy-transfer processes.
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Photoredox Catalysis in Organic Chemistry
TL;DR: This Perspective highlights the unique ability of photoredox catalysis to expedite the development of completely new reaction mechanisms, with particular emphasis placed on multicatalytic strategies that enable the construction of challenging carbon-carbon and carbon-heteroatom bonds.
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Catalytic enantioselective addition to imines.
Shu Kobayashi,Haruro Ishitani +1 more
TL;DR: Shū Kobayashi was born in 1959 in Tokyo, Japan and studied chemistry at the University of Tokyo and received his Ph.D. in 1988 (Professor T. Mukaiyama), and received the first Springer Award in Organometallic Chemistry in 1997.