Journal ArticleDOI
Stress and Immunity: Age Enhances the Risks
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The data suggest that aging interacts with stress and depression to enhance risks for morbidity and mortality among older adults.Abstract:
A competent immune response is central to good health. There is good evidence that both aging and psychological stress can dysregulate immune function, resulting in changes in various aspects of the immune response that are large enough to have consequences for health. Older adults appear to show even greater immunological impairments associated with stress or depression than younger adults. Thus, the data suggest that aging interacts with stress and depression to enhance risks for morbidity and mortality among older adults.read more
Citations
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If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans.
TL;DR: A meta-analysis showed that much of the variability in HPA activity is attributable to stressor and person features, as hormonal activity is elevated at stressor onset but reduces as time passes.
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Loneliness, Social Isolation, and Behavioral and Biological Health Indicators in Older Adults
TL;DR: Both social isolation and loneliness were associated with a greater risk of being inactive, smoking, as well as reporting multiple health-risk behaviors, and social isolation was also positively associated with blood pressure, C-reactive protein, and fibrinogen levels.
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Psychoneuroimmunology: psychological influences on immune function and health.
TL;DR: This review focuses on human psychoneuroimmunology studies published in the past decade and discusses the routes through which psychological factors influence immune function, how a stressor's duration may influence the changes observed, and the health consequences of psychosocially mediated immune dysregulation.
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You Make Me Sick: Marital Quality and Health Over the Life Course*
TL;DR: Findings fit with recent theoretical work on cumulative adversity in that marital strain seems to have a cumulative effect on health over time—an effect that produces increasing vulnerability to marital strain with age.
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Advances in Families and Health Research in the 21st Century
Deborah Carr,Kristen W. Springer +1 more
TL;DR: The authors reviewed research on families and health published between 2000 and 2009 and highlight key themes and findings from innovative, methodologically rigorous studies, and pointed out limitations in current research, discuss implications of recent findings for policy, and highlight theoretical and methodological directions for future research.
References
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The relationship between social support and physiological processes: a review with emphasis on underlying mechanisms and implications for health.
TL;DR: Recommendations and directions for future research include the importance of conceptualizing social support as a multidimensional construct, examination of potential mechanisms across levels of analyses, and attention to the physiological process of interest.
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The Neuroendocrinology of Stress and Aging: The Glucocorticoid Cascade Hypothesis*
TL;DR: The goal in the study of aging is not to halt the aging process, because we can no more be cured of aging than of birth as mentioned in this paper, but to slow and soften the sharpest edges of the biological unraveling that constitutes aging.
Journal Article
The Neuroendocrinology of Stress and Aging: The Glucocorticoid Cascade Hypothesis
TL;DR: The goal in the study of aging is not to halt the process, because the authors can no more be cured of aging than of birth, but to slow and soften the sharpest edges of the biological unraveling that constitutes aging.
Journal ArticleDOI
Slowing of wound healing by psychological stress
TL;DR: The effects of psychological stress, caused by caring for a relative with Alzheimer's disease, on wound healing are investigated and stress-related defects in wound repair could have important clinical implications, for instance for recovery from surgery.
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Spousal caregivers of dementia victims: longitudinal changes in immunity and health.
TL;DR: Caregivers who reported lower levels of social support at intake and who were most distressed by dementia‐related behaviors showed the greatest and most uniformly negative changes in immune function at follow‐up.