Strong and small: strong cation-exchange solid-phase extractions using porous polymer monoliths on a digital microfluidic platform
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In this paper, the first method for digital microfluidics-based strong cation-exchange solid-phase extractions is presented, where liquid droplets are separated into different phases.Abstract:
We present the first method for digital microfluidics-based strong cation-exchange solid-phase extractions. Digital microfluidics is a microscale fluid handling technique in which liquid droplets a...read more
Citations
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A review of digital microfluidics as portable platforms for lab-on a-chip applications.
TL;DR: The most recent advances in the DMF platforms are discussed, and the feasibility of developing multifunctional packages for performing complete sets of processes of biochemical assays, particularly for point-of-care applications is evaluated.
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An inkjet printed, roll-coated digital microfluidic device for inexpensive, miniaturized diagnostic assays
TL;DR: A new digital microfluidic (DMF) platform fabricated using a custom inkjet printing and roll-coating process that is scalable to mass production is introduced, lowering the costs to a level such that the new platforms will be an attractive alternative to LFAs for the diagnosis of infectious disease at the POC.
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Digital microfluidic platform for human plasma protein depletion.
TL;DR: This work presents a method of protein depletion using superparamagnetic beads coated in anti-HSA, Protein A, and Protein G, manipulated by digital microfluidics (DMF), which resulted in an approximately 4-fold increase in signal-to-noise ratio in MALDI-MS analysis for a low abundance protein, hemopexin.
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Exploring bubble oscillation and mass transfer enhancement in acoustic-assisted liquid-liquid extraction with a microfluidic device
Yuliang Xie,Chandraprakash Chindam,Nitesh Nama,Shikuan Yang,Mengqian Lu,Yanhui Zhao,John D. Mai,Francesco Costanzo,Tony Jun Huang +8 more
TL;DR: The acoustic streaming induced by the bubble oscillation was identified as the cause of this enhanced extraction and the enhanced efficiency in mass transport via these acoustic-energy-assisted processes was confirmed by comparisons against a pure diffusion-based process.
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Direct loading of blood for plasma separation and diagnostic assays on a digital microfluidic device
TL;DR: A new digital microfluidic (DMF) diagnostic platform with integrated porous membranes for blood-plasma separation from finger-stick blood volumes, capable of performing complex, multi-step, diagnostic assays.
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TL;DR: Of more than 700 identified phosphopeptides, 139 were differentially regulated at least 2-fold in response to mating pheromone and among these regulated proteins were components belonging to the mitogen-activated protein kinase signaling pathway and to downstream processes including transcriptional regulation, the establishment of polarized growth, and the regulation of the cell cycle.
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Determination of endocrine-disrupting phenolic compounds and estrogens in surface and drinking water by HRGC-(NCI)-MS in the picogram per liter range.
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