Journal ArticleDOI
Studies of novel pentacyciic heterocyclic steroids: part XXI. Total synthesis of racemic benz[3,4]-6-oxaestra-1,3,5(10),8-tetraen-17β-ol
TLDR
In this article, a racemic benz[3,4]-6-oxaestra-1,3,5(10),8-tetraen-17β-ol in 45% yield was converted into racemic 1.1-oxo-4oxa-4.oxa and 1.2-hexanthrene.About:
This article is published in Steroids.The article was published on 1990-03-01. It has received 4 citations till now. The article focuses on the topics: Yield (chemistry) & Total synthesis.read more
Citations
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Journal ArticleDOI
Synthesis of pentacyclic steroids
TL;DR: A review of literature on the synthesis of pentacyclic steroids is presented and it is shown that the steroids are among the most important secondary metabolites.
Journal ArticleDOI
Novel and efficient synthesis of 22-alkynyl-13,24(23)-cyclo-18,21-dinorchol-22-en-20(23)-one analogues.
TL;DR: Evaluation of the synthesized compounds for cytotoxicity against KB, HeLa, MKN-28 and MCF-7 cell lines showed that the 22-alkynylcyclodinorchoenones possessing hydroxylethyl and hydroxylmethyl mono-substituted side chain at the end of alkynyl group have significantly inhibition activity.
Journal ArticleDOI
Synthesis of new pentacyclic heterocyclic steroidal analogs, 6-oxabenz[3,4]-d-homoestra- 1,3,5(10),8,14-pentaen-17α-one and 3a,4,5,13-tetrahydro-3H- [2]benzothieno[5,4-d]naphtho- [1,2-b]pyran☆
TL;DR: The total synthesis of new pentacyclic heterocyclic steroidal analogs, 6-oxabenz[3,4], 1,3,5(10),8,14-pentaen-17a-one and 3a,4,5,13-tetrahydro-3H-[2]benzothieno[5,4-d]naphtho[1,2-b]-pyran is described.
Journal ArticleDOI
Synthesis of 6-oxaestra-1,3,5(10),8,14-pentaenes
Sh. N. Abusalimov,S. K. Nikol’skaya,Galina L. Starova,Stanislav I. Selivanov,Alexander G. Shavva +4 more
TL;DR: The Wendler version of the Torgov-Ananchenko scheme of total steroid synthesis was shown to be applicable to the preparation of 6-oxaestra-1,3,5(10),8,14-pentaenes, which ensured isolation of the target compounds in a high yield without using chromatographic purification methods.
References
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Journal ArticleDOI
Applications of Ionic Hydrogenation to Organic Synthesis
Journal ArticleDOI
New syntheses of estrone, d,1-8-iso-oestrone and d,1-19-nortestosterone
S.N. Ananchenko,I.V. Torgov +1 more
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Stereospecific Syntheses of trans-1β-Hydroxy-8-methyl-4,5-(4'-methoxybenzo)-hydrindane, trans-1β-Hydroxy-8-methyl-4,5-(3'-methyl-4'-methoxybenzo)- hydrindane and d,l-Equilenin Methyl Ether
Journal ArticleDOI
Total synthesis of derivatives of (±)-6-oxa and aza-estrone
TL;DR: Es wird über die Totalsynthese von verschiedenen Derivaten des (±)-6-Oxa- und Aza-Östrons und die Umwandlung von (±-17β-Oxy-3-methoxy-6-oxa-östratrien-1, 3, 510 zu Verbindungen der (±)19-Nor-6