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Studies of small intestine during development. I. Distribution and activity of beta-galactosidase.
Ruth G. Doell,Norman Kretchmer +1 more
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The hypothesis that s-galactosidase in the fetal intestine is induced by circulating lactose is not supported by the evidence presented.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1962-08-13. It has received 238 citations till now. The article focuses on the topics: Small intestine & Ileum.read more
Citations
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Authentic and artifactual detection of the E. coli lacZ gene product in the rat brain by histochemical methods
William S. Rosenberg,William S. Rosenberg,Xandra O. Breakefield,Carlo DeAntonio,Ole Isacson,Ole Isacson +5 more
TL;DR: Dramatic non-E.
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Intestinal dipeptidases. IV. Studies on the release and subcellular distribution of intestinal dipeptidases of the mucosa cells of the pig.
Lars Josefsson,Hans Sjöström +1 more
TL;DR: In this paper, the distribution of dipeptidases in the subcellular fractions of the mucosa cells has been determined, and the activities are located in the supernatant fraction.
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Genetic test for lactase non-persistence and hydrogen breath test: Is genotype better than phenotype to diagnose lactose malabsorption?
TL;DR: A positive genetic test for lactase non-persistence indicates whether lactase activity decline may represent a clinical problem for the patient, but does not give information on actual patient symptoms.
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A proposed mechanism of normal intestinal lactase decline in the postweaned mammal.
TL;DR: Evidence is presented to support a proposal that temporally related cytokinetic changes, which effect a generally corresponding reduction in enterocyte life-span, serve as the causal basis of lactase decline in the postweaned mammal.
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Maturation of human intestinal lactase-phlorizin hydrolase Generation of the brush border form of the enzyme involves at least two proteolytic cleavage steps
Ralf Jacob,Ilona Radebach,Marcel Wüthrich,Jürgen Grünberg,Erwin E. Sterchi,Hassan Y. Naim,Hassan Y. Naim +6 more
TL;DR: It is proposed that the initial cleavage of proLPH takes place intracellularly at a site further away from Arg868-Ala869, to generate LPH beta initial; LPHbeta is subsequently cleaved extracellularly in the gut lumen, presumably by trypsin, to mature brush border LPH (LPHbeta initial).
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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The digestive function of the epithelium of the small intestine. II. Localization of disaccharide hydrolysis in the isolated brush border portion of intestinal epithelial cells.
David T. Miller,Robert K. Crane +1 more
TL;DR: The epithelial brush border membrane has been isolated as a morphologically distinct entity from homogenates of intestinal mucosa and found to contain virtually all of the invertase and maltase activities of the unfractionated homogenate.
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Defective lactose absorption causing malnutrition in infancy.
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A cytochemical study on the pancreas of the guinea pig. I. Isolation and enzymatic activities of cell fractions.
TL;DR: The incorporation of labelled leucine into the proteins of microsomal subtractions and in those of postmicrosomal fractions was studied comparatively in the pancreas of fasted and fed guinea pigs as well as in the liver and pancrea of fasting animals.