Journal ArticleDOI
Studies of small intestine during development. I. Distribution and activity of beta-galactosidase.
Ruth G. Doell,Norman Kretchmer +1 more
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The hypothesis that s-galactosidase in the fetal intestine is induced by circulating lactose is not supported by the evidence presented.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1962-08-13. It has received 238 citations till now. The article focuses on the topics: Small intestine & Ileum.read more
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Book ChapterDOI
Genetics of lactose digestion in humans
TL;DR: The development of the intricate mechanisms of lactase synthesis in the mammary gland and of lactose digestion in the intestinal tract would run counter to evolutionary economy if lactose did not convey a special selective advantage during the suckling period.
Journal ArticleDOI
Cellular Migration of Intestinal Epithelia in Suckling and Weaned Rats
TL;DR: The morphology and enzyme pattern of the small intestine in the suckling differ from that of the adult rat, and therefore it was decided to compare the rate of cellular migration at these different ages by means of incorporation of tritiated thymidine and histo-autoradiography.
Journal ArticleDOI
Isolation of β-galactosidase and β-glucosidase from brain
TL;DR: Attention is drawn to the use of these enzymes for the hydrolysis of glyco-phingolipids by the combined action of both enzymes in brain tissue extracted from brain tissue and separated from each other.
Journal ArticleDOI
The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes
TL;DR: It is concluded that Blimp1 governs the developmental switch responsible for postnatal intestinal maturation, and key components of the adult enterocyte biochemical signature were substantially and prematurely activated.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
The digestive function of the epithelium of the small intestine. II. Localization of disaccharide hydrolysis in the isolated brush border portion of intestinal epithelial cells.
David T. Miller,Robert K. Crane +1 more
TL;DR: The epithelial brush border membrane has been isolated as a morphologically distinct entity from homogenates of intestinal mucosa and found to contain virtually all of the invertase and maltase activities of the unfractionated homogenate.
Journal ArticleDOI
Defective lactose absorption causing malnutrition in infancy.
Journal ArticleDOI
A cytochemical study on the pancreas of the guinea pig. I. Isolation and enzymatic activities of cell fractions.
TL;DR: The incorporation of labelled leucine into the proteins of microsomal subtractions and in those of postmicrosomal fractions was studied comparatively in the pancreas of fasted and fed guinea pigs as well as in the liver and pancrea of fasting animals.