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Journal ArticleDOI

Studies of small intestine during development. I. Distribution and activity of beta-galactosidase.

Ruth G. Doell, +1 more
- 13 Aug 1962 - 
- Vol. 62, Iss: 2, pp 353-362
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TLDR
The hypothesis that s-galactosidase in the fetal intestine is induced by circulating lactose is not supported by the evidence presented.
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This article is published in Biochimica et Biophysica Acta.The article was published on 1962-08-13. It has received 238 citations till now. The article focuses on the topics: Small intestine & Ileum.

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Citations
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Journal ArticleDOI

Cellular origin of lactase decline in postweaned rats

TL;DR: In this article, the authors measured cellular migration rates and lactase activity along villi of intestines taken from rats of different ages to determine the cellular basis for a developmentally regulated fall in enzyme expression.
Journal ArticleDOI

Lactase activity of microorganisms.

TL;DR: The molds exhibited lowest enzyme activity but highest cell yields, bacteria produced lowest cell yield and maximum enzyme activity, and strains exhibiting very high activity were Saccharomyces fragilis and Streptococcus cremoris.
Journal ArticleDOI

Structural and enzymatic changes during colonic maturation in the fetal and suckling rat.

TL;DR: To assess correlations between cellular differentiation and enzymatic maturation in the developing rat colon, tissue from fetal, suckling, weanling, and adult rats was analyzed by electron microscopy and assayed for lactase, alkaline phosphatase, and sodium-potassium-stimulated adenosine triphosphatase activities.
Journal ArticleDOI

Developmental aspects of cystine transport in rat intestinal segments.

TL;DR: Cystine transport by developing gut is less susceptible to both anoxia and sodium deprivation than the mature gut, and the rate of cyst(e)ine efflux from the gut was more rapid in the 7-day old than in the adult.
Journal ArticleDOI

Intestinal β-galactosidase activities in malabsorption syndromes

TL;DR: It is thought that only one of these s-galactosidases, the particulate enzyme hydrolyzing mainly lactose ("true lactase") plays a physiological role in the intestinal absorption of lactose, while the other, the soluble s- GalACTosidase, might be compared to the lysosomal s-GalactOSidase found in many other tissues.
References
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Journal Article

Protein Measurement with the Folin Phenol Reagent

TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI

The digestive function of the epithelium of the small intestine. II. Localization of disaccharide hydrolysis in the isolated brush border portion of intestinal epithelial cells.

TL;DR: The epithelial brush border membrane has been isolated as a morphologically distinct entity from homogenates of intestinal mucosa and found to contain virtually all of the invertase and maltase activities of the unfractionated homogenate.
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A cytochemical study on the pancreas of the guinea pig. I. Isolation and enzymatic activities of cell fractions.

TL;DR: The incorporation of labelled leucine into the proteins of microsomal subtractions and in those of postmicrosomal fractions was studied comparatively in the pancreas of fasted and fed guinea pigs as well as in the liver and pancrea of fasting animals.
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