Journal ArticleDOI
Studies of small intestine during development. I. Distribution and activity of beta-galactosidase.
Ruth G. Doell,Norman Kretchmer +1 more
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The hypothesis that s-galactosidase in the fetal intestine is induced by circulating lactose is not supported by the evidence presented.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1962-08-13. It has received 238 citations till now. The article focuses on the topics: Small intestine & Ileum.read more
Citations
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Separation and characterisation of N-acetyl-β-glucosaminidases A and P from maternal serum
TL;DR: There was a good correlation between levels of N-acetyl-β-glucosaminidase A in maternal serum and total cord activity, which is Type A, at full term.
Journal ArticleDOI
Intestinal Enzymes: Indicators of Proliferation and Differentiation in the Jejunum
TL;DR: Some intestinal enZymes were assayed which were related to cellular proliferation, cellular differentiation, and lysosomes, which can be used to distinguish the crypt from the villus during healthy or diseased states.
Journal ArticleDOI
Multiplicity of human intestinal disaccharidases. i. chromatographic separation of maltases and of two lactases.
TL;DR: Disaccharidases from normal human intestinal mucosa have been solubilised by “autolysis” and/or papain digestion and have been partially separated by gel filtration on Sephadex G-200.
Journal ArticleDOI
Expression of a full-length cDNA coding for human intestinal lactase-phlorizin hydrolase reveals an uncleaved, enzymatically active, and transport-competent protein.
TL;DR: This work has expressed a full-length cDNA encoding LPH in mammalian COS-1 cells, providing the first conclusive evidence that pro-LPH is an enzymatically active molecule and that the intracellular proteolysis of pro- LPH is not essential for the generation of transport-competent forms of LPH.
Book ChapterDOI
Cytology of Intestinal Epithelial Cells
TL;DR: It is now realized that a wide range of structure at light and electron microscopic levels may accompany apparent clinical and functional intestinal normality.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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The digestive function of the epithelium of the small intestine. II. Localization of disaccharide hydrolysis in the isolated brush border portion of intestinal epithelial cells.
David T. Miller,Robert K. Crane +1 more
TL;DR: The epithelial brush border membrane has been isolated as a morphologically distinct entity from homogenates of intestinal mucosa and found to contain virtually all of the invertase and maltase activities of the unfractionated homogenate.
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Defective lactose absorption causing malnutrition in infancy.
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A cytochemical study on the pancreas of the guinea pig. I. Isolation and enzymatic activities of cell fractions.
TL;DR: The incorporation of labelled leucine into the proteins of microsomal subtractions and in those of postmicrosomal fractions was studied comparatively in the pancreas of fasted and fed guinea pigs as well as in the liver and pancrea of fasting animals.