Journal ArticleDOI
Surfactant systems: Microemulsions and vesicles as vehicles for drug delivery
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TLDR
This review highlights the work to date investigating the potential of microemulsions as drug cariers and also reports on preliminary studies performed on the use of vesicles formed from nonionic surfactants.Abstract:
Although surfactants have been widely used as pharmaceutical adjuvants for many years, it is only relatively recently that their phase structures have been seriously considered as drug delivery vehicles per se. This review highlights the work to date investigating the potential of microemulsions as drug carriers and also reports on preliminary studies performed on the use of vesicles formed from nonionic surfactants.read more
Citations
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Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
Ajay Kumar Gupta,Mona Gupta +1 more
TL;DR: This review discusses the synthetic chemistry, fluid stabilization and surface modification of superparamagnetic iron oxide nanoparticles, as well as their use for above biomedical applications.
Journal ArticleDOI
Microemulsion-based media as novel drug delivery systems
M. Jayne Lawrence,Gareth D. Rees +1 more
TL;DR: The use of microemulsions and closely related microemulsion-based systems as drug delivery vehicles is reviewed, with particular emphasis being placed on recent developments and future directions.
Journal ArticleDOI
Influence of microemulsions on cutaneous drug delivery.
TL;DR: In attempt to increase cutaneous drug delivery, microemulsion vehicles have been more and more frequently employed over recent years and a few studies have indicated that the internal structure of microemulsions should allow free diffusion of the drug to optimise cutaneous delivery from these vehicles.
Journal ArticleDOI
Biological activity and environmental impact of anionic surfactants
TL;DR: The role of anionic surfactants in the environment is ambiguous: they can cause serous environmental pollution with toxic effect on living organisms; otherwise, they can promote the decomposition and/or removal of other inorganic and organic pollutants from the environment.
Journal ArticleDOI
Microemulsion method: A novel route to synthesize organic and inorganic nanomaterials
TL;DR: In this paper, the use of microemulsions for synthesizing and controlling the grain size and morphology of the nanoparticles and at the same time summarize some recent works carried out in the synthesis of organic and inorganic nanoparticles by this method.
References
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Journal ArticleDOI
Theory of self-assembly of hydrocarbon amphiphiles into micelles and bilayers
TL;DR: In this paper, a simple theory is developed that accounts for many of the observed physical properties of micelles, both globular and rod-like, and of bilayer vesicles composed of ionic or zwitterionic amphiphiles.
Journal ArticleDOI
Sterically stabilized liposomes
Martin C. Woodle,Danilo D. Lasic +1 more
TL;DR: The structure-function relationship of PEG-derivatized phosphatidylethanolamine (PEG-PE) has been examined by measurement of blood lifetime and tissue distribution in both mice and rats and Steric stabilization has been proposed as a theoretical basis for the results.
Journal ArticleDOI
Phase behaviour of polyoxyethylene surfactants with water. Mesophase structures and partial miscibility (cloud points)
TL;DR: In this paper, a model phase diagram is deduced which shows phase structure as a function of surfactant volume fraction and micelle curvature, and two separate mechanisms are proposed for the lower consolute behaviour of polyoxyethylene (CnEOm) + water solutions (the cloud point).
Journal ArticleDOI
Micelles, vesicles and microemulsions
D. John Mitchell,Barry W. Ninham +1 more
TL;DR: In this article, a theory of self-assembly of surfactant molecules into micelles and bilayers is critically examined and extended to include vesicles and microemulsions.
Book
Colloidal Drug Delivery Systems
TL;DR: Ointments and creams as colloidal drug delivery systems microemulsions liposomes niosomes nanoparticles niosome nanoparticles.