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Surgical Treatment of Colon Cancer of the Splenic Flexure: A Systematic Review and Meta-analysis

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TLDR
In conclusion, the optimal extent of SFC surgical resection, that is, ERC or LC remains under debate, however, laparoscopy provides better postoperative outcomes and fewer postoperative complications than open surgery.
Abstract
This is a systematic review and meta-analysis on the surgical treatments of splenic flexure carcinomas (SFCs). Medline, EMBASE, and Scopus were searched from January 1990 to May 2016. Studies of at least 5 patients comparing extended right colectomy (ERC) versus left colectomy (LC) and/or laparoscopy versus open surgery for SFCs were retrieved and analyzed. Overall, 12 retrospective studies were selected, including 569 patients. ERC was performed in 23.2% of patients, whereas LC in 76.8%. Pooled data suggested that ERC and LC had similar oncologic quality of resection and postoperative outcomes. Laparoscopy was used in 50.6% of patients (conversion rate: 2.5%) and it was associated with significantly shorter time to oral diet, fewer postoperative complications, and shorter hospital stay than open surgery. In conclusion, the optimal extent of SFC surgical resection, that is, ERC or LC remains under debate. However, laparoscopy provides better postoperative outcomes and fewer postoperative complications than open surgery.

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The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Colon Cancer

TL;DR: The American Society of Colon and Rectal Surgeons (ASCRS) as mentioned in this paper developed a set of guidelines for the management of colorectal cancer, which are intended for the use of all practitioners, health care workers, and patients who desire information about the conditions addressed by the topics covered in these guidelines.
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Propensity score analysis of postoperative and oncological outcomes after surgical treatment for splenic flexure colon cancer

TL;DR: The short and long-term outcomes between ERC, SLC, and LC are similar and SLC should be considered oncologically as appropiate as the other more extensive resections.
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Optimal Surgery for Mid-Transverse Colon Cancer: Laparoscopic Extended Right Hemicolectomy Versus Laparoscopic Transverse Colectomy.

TL;DR: Laparoscopic extended right hemicolectomy and laparoscopic transverse colectomy offer similar oncological outcomes for mid-transverse colon cancer and might be associated with fewer postoperative complications.
References
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Journal ArticleDOI

Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement

TL;DR: A structured summary is provided including, as applicable, background, objectives, data sources, study eligibility criteria, participants, interventions, study appraisal and synthesis methods, results, limitations, conclusions and implications of key findings.
Journal ArticleDOI

GRADE: an emerging consensus on rating quality of evidence and strength of recommendations

TL;DR: The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.
Journal ArticleDOI

Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial

TL;DR: Laroscopic-assisted surgery for cancer of the colon is as effective as open surgery in the short term and is likely to produce similar long-term outcomes, however, impaired short- term outcomes after laparosc-assisted anterior resection forcancer of the rectum do not yet justify its routine use.
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