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Journal ArticleDOI

Synthesis, characterisation and potential application of deoxycholic acid carboxymethyl chitosan as a carrier agent for rotenone

TLDR
In this paper, deoxycholic acid carboxymethyl chitosan (DACMC) was synthesized via a two-step reaction, namely carboxy methylation and alkylation.
Abstract
In the present study, deoxycholic acid carboxymethyl chitosan (DACMC) was synthesised via a two-step reaction, namely carboxymethylation and alkylation. Fourier Transform Infrared (FTIR) Spectrometer, Proton Nuclear Magnetic Resonance (1H NMR) Spectrometer, Transmission Electron Microscope (TEM) and Thermogravimetric Analyser (TGA) were used to characterise DACMC. Spherical self-aggregates of DACMC micelles with the size ranging from 91.3 to 140.0 nm was observed. DACMC was soluble in pH range studied (1–13), except pH 4. DACMC micelles were formed at critical concentration (CMC) value of 0.468 mg/mL. The ability of DACMC to encapsulate and load rotenone was determined at different weight ratios. The highest value of encapsulation efficiency (EE%) (more than 98%) was obtained for weight ratio of 100:1 (DACMC:Rotenone). The in vitro release data of rotenone-loaded DACMC followed Ritger and Peppas Case II transport mechanism. Results from this study highlight the potential of DACMC to reduce organic solvent application in water-insoluble pesticide production.

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Citations
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Book ChapterDOI

Bioactivity of Nanoformulated Synthetic and Natural Insecticides and Their Impact on Environment

TL;DR: This chapter gives a comprehensive overview of recent findings related to the bioactivity of nanoformulations of synthetic and natural insecticides against harmful insects causing severe damage to economically important crops or deteriorating stored food products.
Journal ArticleDOI

Negative effects of a piscicide, rotenone, on the growth and metabolism of three submerged macophytes

TL;DR: It is highlighted that submerged species may be greatly suppressed by RT, and RT should be applied in water ecosystems with great caution.
Journal ArticleDOI

Synthesis of rotenone loaded zein nano-formulation for plant protection against pathogenic microbes

TL;DR: In this article, the authors showed that rotenone loaded in zein nanoparticles (ZSC) showed self-assembled spherical nanostructures having 425.67 ± 7.02 and 471.33 ± 10.60 nm of hydrodynamic radii with −14.23 ± 0.21 and −17.64 ± 0.89 mV zeta potential for ZSC and RNZSC, respectively.
References
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Journal ArticleDOI

A simple equation for description of solute release II. Fickian and anomalous release from swellable devices

TL;DR: In this paper, an exponential relation M t /M ∞ = kt n may be used to describe the Fickian and non-Fickian release behavior of release systems which are prepared by incorporation of a drug in a hydrophilic, initially glassy polymer.
Journal ArticleDOI

Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC).

TL;DR: The present article is a comprehensive review of the current state of the art of mathematical modeling drug release from HPMC-based delivery systems and discusses the crucial points of the most important theories.
Journal ArticleDOI

A simple equation for the description of solute release. III. Coupling of diffusion and relaxation

TL;DR: In this paper, a coupled diffusion/relaxation model is presented for general analysis of the release behavior of controlled release systems using a coupled diffusional and relaxation model, and the general form of this equation's exponent is related to the geometric shape of the releasing device through its aspect ratio.
Journal ArticleDOI

On the determination of the critical micelle concentration by the pyrene 1:3 ratio method

TL;DR: In this paper, a simple and accurate approach to the treatment of pyrene 1:3 ratio data in the context of critical micelle concentration determination in surfactant solutions is established.
Journal ArticleDOI

Chemical characteristics of O-carboxymethyl chitosans related to the preparation conditions

TL;DR: In this article, the water insolubility of carboxymethyl chitosans at various pHs varied with the degree of the carboxyethylation and the reaction temperature, and the ratio of water/isopropanol in the reaction solvent.
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