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Open AccessJournal ArticleDOI

Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome

TLDR
The terlipressin is used for type 1 hepatorenal syndrome (HRS-1) in many parts of the world and is part of the clinical practice guidelines in Europe as discussed by the authors.
Abstract
Background The vasoconstrictor terlipressin is used for type 1 hepatorenal syndrome (HRS-1) in many parts of the world and is part of the clinical practice guidelines in Europe. Methods We...

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Journal ArticleDOI

Acute-on-Chronic Liver Failure Clinical Guidelines

TL;DR: These guidelines indicate the preferred approach to the management of patients with acute-on-chronic liver failure and represent the official practice recommendations of the American College of Gastroenterology.
Journal ArticleDOI

Terlipressin use and respiratory failure in patients with hepatorenal syndrome type 1 and severe acute‐on‐chronic liver failure

TL;DR: This data indicates that liver transplantation in patients with hepatorenal syndrome type 1 (HRS1) and advanced acute‐on‐chronic liver failure (ACLF) requires further study to establish a causative mechanism.
Journal ArticleDOI

Norepinephrine is More Effective Than Midodrine/Octreotide in Patients With Hepatorenal Syndrome-Acute Kidney Injury: A Randomized Controlled Trial.

TL;DR: In this article, the authors compared the efficacy of midodrine/octreotide to that of norepinephrine for the treatment of patients with hepatorenal syndrome and found that nore pinephrine plus albumin is significantly more effective in improving renal function in patients with liver failure.
Journal ArticleDOI

Feasibility and Effectiveness of Norepinephrine Outside the Intensive Care Setting for Treatment of Hepatorenal Syndrome.

TL;DR: In this paper, the authors evaluated the real-life effectiveness of a sequential vasoconstrictor regimen of midodrine-Octreotide followed by norepinephrine in a nonintensive care unit (non-ICU) setting in the United States, where terlipressin is not available.
Journal ArticleDOI

Review article: current and emerging therapies for the management of cirrhosis and its complications

TL;DR: Cirrhosis is increasingly common and morbid and optimal utilisation of therapeutic strategies to prevent and control the complications of cirrhosis are central to improving clinical and patient‐reported outcomes.
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