Acute-on-Chronic Liver Failure Clinical Guidelines
Jasmohan S. Bajaj,Jacqueline G. O'Leary,Jennifer C. Lai,Florence Wong,Millie D. Long,Robert J. Wong,Patrick S. Kamath +6 more
TLDR
These guidelines indicate the preferred approach to the management of patients with acute-on-chronic liver failure and represent the official practice recommendations of the American College of Gastroenterology.About:
This article is published in The American Journal of Gastroenterology.The article was published on 2022-01-10 and is currently open access. It has received 62 citations till now. The article focuses on the topics: Medicine & Medicine.read more
Citations
More filters
Journal ArticleDOI
Acute-on-chronic liver failure (ACLF) in 2022: have novel treatment paradigms already arrived?
TL;DR: This disease has clear pathogenesis and epidemiological burden, thus distinguishing it from decompensated cirrhosis; there is clear clinical need for the development of specific and nuanced therapies to treat this condition.
Journal ArticleDOI
Management of Decompensated Cirrhosis in the Surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document
Anupamaa J Seshadri,Rachel Appelbaum,Samuel P. Carmichael,Joseph Cuschieri,J. Jason Hoth,Krista L. Kaups,Lisa M. Kodadek,Matthew E. Kutcher,Abhijit Pathak,Joseph F. Rappold,Sean Rudnick,Christopher P. Michetti +11 more
TL;DR: This Clinical Consensus Document created by the American Association for the Surgery of Trauma Critical Care Committee reviews practical clinical questions about the critical care management of patients with decompensated cirrhosis to facilitate best practices by the bedside provider.
Journal ArticleDOI
Inadequate practices for hepatic encephalopathy management in the inpatient setting
TL;DR: Overall effective management of Hepatic encephalopathy calls for attention to guideline‐directed nutritional requirements, functional assessment, medication reconciliation, patient education/counseling, and proper discharge planning.
Journal ArticleDOI
Hepatic perfusion as a new predictor of prognosis and mortality in critical care patients with acute-on-chronic liver failure
Johannes Vogg,Constantin Maier-Stocker,Stefan Munker,Alexander Mehrl,S Schlosser,H. Tews,Karsten Gülow,Martina Müller,S Schmid +8 more
TL;DR: The prognostic value of the assessment of hepatic perfusion in critical care patients with severe liver diseases by bedside Doppler ultrasound examination is shown and its utility as an accurate predictor of the outcome in patients with ACLF is shown.
Journal ArticleDOI
Current and future perspectives on acute-on-chronic liver failure: Challenges of transplantation, machine perfusion, and beyond
Bianca Della Guardia,Amanda P. C. S. Boteon,Celso Eduardo Lourenço Matielo,Guilherme Eduardo Gonçalves Felga,Yuri L. Boteon +4 more
TL;DR: In this paper , an urgent and global discussion about allocation and prioritization for transplantation in critically ill acute-on-chronic liver failure patients is needed because there is evidence suggesting that the current model may not portray their wait-list mortality.
References
More filters
Journal ArticleDOI
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
Mervyn Singer,Clifford S. Deutschman,Christopher W. Seymour,Manu Shankar-Hari,Djillali Annane,Michael Bauer,Rinaldo Bellomo,Gordon R. Bernard,Jean-Daniel Chiche,Craig M. Coopersmith,Richard S. Hotchkiss,Mitchell M. Levy,John C. Marshall,Greg S. Martin,Steven M. Opal,Gordon D. Rubenfeld,Gordon D. Rubenfeld,Tom van der Poll,Jean Louis Vincent,Derek C. Angus +19 more
TL;DR: The task force concluded the term severe sepsis was redundant and updated definitions and clinical criteria should replace previous definitions, offer greater consistency for epidemiologic studies and clinical trials, and facilitate earlier recognition and more timely management of patients with sepsi or at risk of developing sepsic shock.
Journal ArticleDOI
GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables
Gordon H. Guyatt,Andrew D Oxman,Elie A. Akl,Regina Kunz,Gunn Elisabeth Vist,Jan Brozek,Susan L Norris,Yngve Falck-Ytter,Paul Glasziou,Hans deBeer,Roman Jaeschke,David Rind,Joerg J Meerpohl,Philipp Dahm,Holger J. Schünemann +14 more
TL;DR: The GRADE process begins with asking an explicit question, including specification of all important outcomes, and provides explicit criteria for rating the quality of evidence that include study design, risk of bias, imprecision, inconsistency, indirectness, and magnitude of effect.
Journal ArticleDOI
GRADE guidelines: 3. Rating the quality of evidence
Howard Balshem,Mark Helfand,Mark Helfand,Holger J. Schünemann,Andrew D Oxman,Regina Kunz,Jan Brozek,Gunn Elisabeth Vist,Yngve Falck-Ytter,Joerg J Meerpohl,Susan L Norris,Gordon H. Guyatt +11 more
TL;DR: The approach of GRADE to rating quality of evidence specifies four categories-high, moderate, low, and very low-that are applied to a body of evidence, not to individual studies.
Journal ArticleDOI
Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis
Richard Moreau,Rajiv Jalan,Pere Ginès,Marco Pavesi,Paolo Angeli,Juan Córdoba,François Durand,Thierry Gustot,Faouzi Saliba,Marco Domenicali,Alexander L. Gerbes,Julia Wendon,Carlo Alessandria,Wim Laleman,Stefan Zeuzem,Jonel Trebicka,Mauro Bernardi,Vicente Arroyo +17 more
TL;DR: Diagnostic criteria for ACLF was established and showed that it is distinct from AD, based not only on the presence of organ failure(s) and high mortality rate but also on age, precipitating events, and systemic inflammation.
Journal ArticleDOI
Effect of Intravenous Albumin on Renal Impairment and Mortality in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis
Pau Sort,Miquel Navasa,Vicente Arroyo,Xavier Aldeguer,Ramon Planas,Luis Ruiz-del-Arbol,Lluis Castells,Victor Vargas,Germán Soriano,Mónica Guevara,Pere Ginès,Joan Rodés +11 more
TL;DR: In patients with cirrhosis and spontaneous bacterial peritonitis, treatment with intravenous albumin in addition to an antibiotic reduces the incidence of renal impairment and death in comparison with treatment with an antibiotic alone.
Related Papers (5)
[EASL clinical practice guidelines: prevention and treatment of hemorrhage and thrombosis in liver cirrhosis].
Bohai Luo,Gi-Hoon Han +1 more