The components of membrane conductance in the giant axon of Loligo.
A. L. Hodgkin,A. F. Huxley +1 more
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This article is published in The Journal of Physiology.The article was published on 1952-04-28 and is currently open access. It has received 1349 citations till now. The article focuses on the topics: Giant axon & Loligo.read more
Citations
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Journal ArticleDOI
A quantitative description of membrane current and its application to conduction and excitation in nerve
A. L. Hodgkin,A. F. Huxley +1 more
TL;DR: This article concludes a series of papers concerned with the flow of electric current through the surface membrane of a giant nerve fibre by putting them into mathematical form and showing that they will account for conduction and excitation in quantitative terms.
Book
The synaptic organization of the brain
TL;DR: Introduction to synaptic circuits, Gordon M.Shepherd and Christof Koch membrane properties and neurotransmitter actions, David A.Brown and Anthony M.Brown.
Journal ArticleDOI
Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo
A. L. Hodgkin,A. F. Huxley +1 more
TL;DR: The identity of the ions which carry the various phases of the membrane current is chiefly concerned with sodium ions, since there is much evidence that the rising phase of the action potential is caused by the entry of these ions.
Journal ArticleDOI
Electrical stimulation of excitable tissue: design of efficacious and safe protocols.
TL;DR: The physical basis for electrical stimulation of excitable tissue, as used by electrophysiological researchers and clinicians in functional electrical stimulation, is presented with emphasis on the fundamental mechanisms of charge injection at the electrode/tissue interface.
References
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Journal ArticleDOI
Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo
A. L. Hodgkin,A. F. Huxley +1 more
TL;DR: The identity of the ions which carry the various phases of the membrane current is chiefly concerned with sodium ions, since there is much evidence that the rising phase of the action potential is caused by the entry of these ions.
Journal ArticleDOI
Measurement of current-voltage relations in the membrane of the giant axon of Loligo.
TL;DR: The importance of ionic movements in excitable tissues has been emphasized by a number of recent experiments which are consistent with the theory that nervous conduction depends on a specific increase in permeability which allows sodium ions to move from the more concentrated solution outside a nerve fibre to the more dilute solution inside it.
Journal ArticleDOI
The ionic basis of electrical activity in nerve and muscle
TL;DR: This hypothesis is applied to the phenomena of subthreshold activity, accomodation and oscillatory behaviour and it is suggested that both permeability changes vary with membrane potential in a graded but reversible manner.
Journal ArticleDOI
The effect of temperature on the electrical activity of the giant axon of the squid
A. L. Hodgkin,B. Katz +1 more
TL;DR: It is important to know whether the characteristic relation between action potential and resting potential holds over a wide range of temperature, and the use of an internal recording electrode facilitates this study.
Related Papers (5)
Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo
A. L. Hodgkin,A. F. Huxley +1 more
A quantitative description of membrane current and its application to conduction and excitation in nerve
A. L. Hodgkin,A. F. Huxley +1 more
The effect of sodium ions on the electrical activity of the giant axon of the squid
A. L. Hodgkin,B. Katz +1 more