scispace - formally typeset
Journal ArticleDOI

The covalent structure of dog myoglobin.

Viviane Dumur, +2 more
- 20 Feb 1976 - 
- Vol. 420, Iss: 2, pp 376-386
TLDR
The primary structure of the myoglobin of the domestic dog (German shepherd) was studied and shows 16 differences versus badger, 20 versus harbour seal and 15 versus California sea lion.
About
This article is published in Biochimica et Biophysica Acta.The article was published on 1976-02-20. It has received 14 citations till now. The article focuses on the topics: Myoglobin & Globin.

read more

Citations
More filters
Journal ArticleDOI

Fitting the Gene Lineage into its Species Lineage, a Parsimony Strategy Illustrated by Cladograms Constructed from Globin Sequences

TL;DR: In this article, it was shown that the gene lineages deviate relatively little from established species relationships, and that most contemporary gene pairs in this phylogenetic system may be regarded as orthologous rather than paralogous (split at the time of speciation) rather than split prior to speciation, and it also appeared that as the statistical sample of orthologyous sequence sites becomes greatly enlarged by tandem alignment of enough different types of protein chains, the parsimony reconstruction based strictly on minimal nucleotide replacement length will itself reveal the correct cladogram for the set of contemporary species
Journal ArticleDOI

Effects of amino acid substitutions outside an antigenic site on protein binding to monoclonal antibodies of predetermined specificity obtained by peptide immunization: demonstration with region 94-100 (antigenic site 3) of myoglobin.

TL;DR: The results indicate that the reaction of mAbs, whose specificity is precisely known and predetermined by the immunizing free peptide, can be markedly affected by substitutions outside the indicated binding region on the protein.
Journal ArticleDOI

Evolution of mammalian diving capacity traced by myoglobin net surface charge.

TL;DR: The convergent evolution of high myoglobin net surface charge in mammalian divers increases intermolecular electrostatic repulsion, permitting higher muscle oxygen storage capacities without potentially deleterious self-association of the protein.
Journal ArticleDOI

Topographic antigenic determinants recognized by monoclonal antibodies to sperm whale myoglobin.

TL;DR: These determinants differ from previously reported antigenic sites on sperm whale myoglobin both in that they are topographic, rather than sequential, and in that almost all the critical residues recognized by these antibodies are outside the previously reported sites.
Journal ArticleDOI

On the evolution of myoglobin.

TL;DR: Estimates of the rate of molecular evolution are of interest because its supposed constancy has been a major argument in favour of the hypothesis that a high proportion of fixed mutations are neutral, or nearly so, as far as selection is concerned.
References
More filters
Journal ArticleDOI

A Protein Sequenator

P. Edman, +1 more
- 01 Mar 1967 - 
TL;DR: The protein sequenator is an instrument for the automatic determination of amino acid sequences in proteins and peptides that operates on the principle of the phenylisothiocyanate degradation scheme and has been applied to the whole molecule of apomyoglobin from the humpback whale.
Journal ArticleDOI

Strategy and tactics in protein chemistry.

B S Hartley
- 01 Oct 1970 - 
Journal ArticleDOI

Structure covalente de la myoglobine de cheval

TL;DR: Several sequences which could be previously deduced from the study of split products after cyanogen bromide treatment were confirmed, and the specificity of chymotrypsin towards certain types of peptide bonds is discussed.
Related Papers (5)