The current status of opisthorchiasis and clonorchiasis in the Mekong Basin.
Paiboon Sithithaworn,Ross H. Andrews,Nguyen Van De,Thitima Wongsaroj,Muth Sinuon,Peter Odermatt,Yukifumi Nawa,Song Liang,Paul J. Brindley,Banchob Sripa +9 more
TLDR
It is disturbing that despite treatment and control programs in place for decades, all countries of the Lower Mekong Basin are still highly endemic with O. viverrini and/or C. sinensis as well as alarmingly high levels of CCA incidence.About:
This article is published in Parasitology International.The article was published on 2012-03-01 and is currently open access. It has received 332 citations till now. The article focuses on the topics: Clonorchiasis & Opisthorchis viverrini.read more
Citations
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The tumorigenic liver fluke Opisthorchis viverrini – multiple pathways to cancer
Banchob Sripa,Paul J. Brindley,Jason Mulvenna,Thewarach Laha,Michael J. Smout,Eimorn Mairiang,Jeffrey M. Bethony,Alex Loukas +7 more
TL;DR: A schema for human disease progression from fluke infection, chronic opisthorchiasis, advanced periductal fibrosis, and cholangiocarcinogenesis is reviewed, and a rationale for biomarker discovery to facilitate early intervention is presented.
Book
Sustaining the drive to overcome the global impact of neglected tropical diseases : second WHO report on neglected tropical diseases
TL;DR: Second WHO report on neglected tropical diseases builds on the growing sense of optimism generated by the 2012 publication of the WHO Roadmap and escalated since 2010, as have donations of medicines from pharmaceutical companies and the engagement of the scientific community.
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Roles of liver fluke infection as risk factor for cholangiocarcinoma.
Paiboon Sithithaworn,Puangrat Yongvanit,Kunyarat Duenngai,Nadda Kiatsopit,Chawalit Pairojkul +4 more
TL;DR: Current knowledge of the biology, life cycle, and pathogenesis of O. viverrini, and its role as a carcinogenic parasite are presented and the trends of age‐specific incidence of liver cancer in Khon Kaen, northeast Thailand are considered.
Journal ArticleDOI
The zoonotic, fish-borne liver flukes Clonorchis sinensis, Opisthorchis felineus and Opisthorchis viverrini.
Trevor N. Petney,Ross H. Andrews,Ross H. Andrews,Weerachai Saijuntha,Alexandra Wenz-Mücke,Paiboon Sithithaworn +5 more
TL;DR: The comparative epidemiology of these three taxa comparing in detail the use of first, second and final animal hosts, and the potential role of humans in spreading these pathogens is considered.
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The global epidemiology of clonorchiasis and its relation with cholangiocarcinoma
TL;DR: The epidemiology of clonorchiasis is characterized by rising trend in its prevalence, variability among sexes and age, as well as endemicity in different regions, and it is worthwhile to carry out further epidemiological studies.
References
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Clonorchiasis: a key foodborne zoonosis in China
TL;DR: A background on the parasite and its life cycle is provided, key aspects regarding the pathogenesis, diagnosis, and treatment of clonorchiasis are summarized, the geographic distribution and prevalence are described, and some recommendations for future research and the control of this important disease are made.