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The global epidemiology of clonorchiasis and its relation with cholangiocarcinoma

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TLDR
The epidemiology of clonorchiasis is characterized by rising trend in its prevalence, variability among sexes and age, as well as endemicity in different regions, and it is worthwhile to carry out further epidemiological studies.
Abstract
This paper reviews the epidemiological status and characteristics of clonorchiasis at global level and the etiological relationship between Clonorchis sinensis infection and cholangiocarcinoma (CCA). A conservative estimation was made that 15 million people were infected in the world in 2004, of which over 85% distributed in China. The epidemiology of clonorchiasis is characterized by rising trend in its prevalence, variability among sexes and age, as well as endemicity in different regions. More data indicate that C. sinensis infection is carcinogenic to human, and it is predicted that nearly 5 000 CCA cases attributed to C. sinensis infection may occur annually in the world decades later, with its overall odds ratio of 4.47. Clonorchiasis is becoming one major public health problem in east Asia, and it is worthwhile to carry out further epidemiological studies.

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Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015

Haidong Wang, +844 more
- 08 Oct 2016 - 
TL;DR: The Global Burden of Disease 2015 Study provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015, finding several countries in sub-Saharan Africa had very large gains in life expectancy, rebounding from an era of exceedingly high loss of life due to HIV/AIDS.

为 cholangiocarcinoma 的化疗: 更改

TL;DR: There are limited data and the role of adjuvant chemotherapy/chemoradiation in patients with resected biliary tract cancer is poorly defined, and no neoadjuvant therapy can be considered a standard approa.
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Elimination of tropical disease through surveillance and response

TL;DR: Six different research priorities have been identified: dynamic mapping of transmission, near real-time capture of population dynamics, modelling based on a minimum essential database/dataset, implementation of mobile health and sensitive diagnostics, design of effective response packages tailored to different transmission settings and levels, and validation of approaches and responses packages.
Journal ArticleDOI

Current status of Clonorchis sinensis and clonorchiasis in China

TL;DR: The status of clonorchiasis in China is described, including diagnosis techniques, pathogenesis and genome/transcriptome/proteome studies in the last years, and the major advances in the field of clonsporchiasis research during last decade are summarized.
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Research gaps for three main tropical diseases in the People’s Republic of China

TL;DR: These three diseases: schistosomiasis japonica, malaria and echinococcosis are analyzed and it is believed these three diseases can eventually be eliminated in mainland China if all the research gaps are abridged in a short period of time.
References
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IARC Monographs on the Evaluation of Carcinogenic Risks to Humans

TL;DR: This timely monograph is a distillation of knowledge of hepatitis B, C and D, based on a review of 1000 studies by a small group of scientists, and it is concluded that hepatitis D virus cannot be classified as a human carcinogen.
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The global health burden of infection-associated cancers in the year 2002.

TL;DR: The fraction of the different types of cancer, and of all cancers worldwide and in different regions, has been estimated using several methods; primarily by reviewing the evidence for the strength of the association (relative risk) and the prevalence of infection in different world areas.
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A review of human carcinogens--Part B: biological agents

TL;DR: In this paper, the carcinogenicity of the biological agents classifi ed as "carcinogenic to humans" (Group 1) and to identify additional tumour sites and mechanisms of carcinogenesis (tables 1 and 2).
Journal ArticleDOI

The epidemiology of cholangiocarcinoma.

TL;DR: Some data point to a potential role for chronic liver disease, hepatitis C, and probably hepatitis B infections in the development of ICC, as well as the recent increasing trends of ICC in the United States.
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