The design of responsive luminescent lanthanide probes and sensors.
TLDR
In this article, the principles of the design of responsive luminescent probes and sensors based on lanthanide emission are summarised, based on a mechanistic understanding of their mode of action.Abstract:
The principles of the design of responsive luminescent probes and sensors based on lanthanide emission are summarised, based on a mechanistic understanding of their mode of action. Competing kinetic pathways for deactivation of the excited states that occur are described, highlighting the need to consider each of the salient quenching processes. Such an analysis dictates the choice of both the ligand and its integral sensitising moiety for the particular application. The key aspects of quenching involving electron transfer and vibrational and electronic energy transfer are highlighted and exemplified. Responsive systems for pH, pM, pX and pO2 and selected biochemical analytes are distinguished, according to the nature of the optical signal observed. Signal changes include both simple and ratiometric intensity measurements, emission lifetime variations and the unique features associated with the observation of circularly polarised luminescence (CPL) for chiral systems. A classification of responsive lanthanide probes is introduced. Examples of the operation of probes for reactive oxygen species, citrate, bicarbonate, α1-AGP and pH are used to illustrate reversible and irreversible transformations of the ligand constitution, as well as the reversible changes to the metal primary and secondary coordination sphere that sensitively perturb the ligand field. Finally, systems that function by modulation of dynamic quenching of the ligand or metal excited states are described, including real time observation of endosomal acidification in living cells, rapid urate analysis in serum, accurate temperature assessment in confined compartments and high throughput screening of drug binding to G-protein coupled receptors.read more
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References
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Journal ArticleDOI
Luminescent chemodosimeters for bioimaging.
TL;DR: Key Laboratory for Organic Electronics and Information Displays (KLOEID) and Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, Nanjing 210046, P. R. China.
Journal ArticleDOI
Interpretation of europium(III) spectra
TL;DR: The trivalent europium ion (Eu3+) is well known for its strong luminescence in the red spectral region, but this ion is also interesting from a theoretical point of view as mentioned in this paper.
Journal ArticleDOI
Lanthanide ion probes of structure in biology. Laser-induced luminescence decay constants provide a direct measure of the number of metal-coordinated water molecules
Journal ArticleDOI
Non-radiative deactivation of the excited states of europium, terbium and ytterbium complexes by proximate energy-matched OH, NH and CH oscillators: an improved luminescence method for establishing solution hydration states
Andrew Beeby,Ian M. Clarkson,Rachel S. Dickins,Stephen Faulkner,David Parker,Louise Royle,Alvaro S. de Sousa,J. A. Gareth Williams,Mark Woods +8 more
TL;DR: In this article, the radiative rate constants for depopulation of the excited states of closely-related series of anionic, neutral and cationic europium, terbium and ytterbium complexes have been measured in H2O and D2O.
Journal ArticleDOI
On the design of highly luminescent lanthanide complexes
TL;DR: In this paper, a review of the design of highly luminescent lanthanide complexes is presented, where the authors discuss all aspects needing optimization, including the various energy migration processes in luminescence sensitization by organic ligands, minimizing non-radiative deactivation mechanisms, as well as other parameters such as the radiative lifetime, the refractive index, and the benefit of inserting luminecent complexes into inorganic-hybrid structures.