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Journal ArticleDOI

The Development of Human Benign Prostatic Hyperplasia with Age

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TLDR
The prevalence and growth rate of human benign prostatic hyperplasia with age is reported by combining and analyzing data from 10 independent studies containing more than 1,000 prostates.
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This article is published in The Journal of Urology.The article was published on 1984-09-01. It has received 2149 citations till now. The article focuses on the topics: Hyperplasia & Prostatectomy.

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The Oxytocin Receptor System: Structure, Function, and Regulation

TL;DR: The regulation by gonadal and adrenal steroids is one of the most remarkable features of the OT system and is, unfortunately, the least understood.
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Serum prostate-specific antigen in a community-based population of healthy men. Establishment of age-specific reference ranges.

TL;DR: The influence of patient age and prostatic size on the serum PSA concentration was assessed in order to use PSA more appropriately to detect clinically significant prostate cancer at an early, potentially curable stage.
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Biologically active dihydropyrimidones of the Biginelli-type--a literature survey.

TL;DR: This review highlights recent developments in the synthesis of functionalized 3,4-dihydropyrimidin-2(1H)-ones with a focus on the DHPMs recently developed as calcium channel modulators, alpha(1a) adrenoceptor-selective antagonists and compounds that target the mitotic machinery.
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Screening for prostate cancer.

TL;DR: There is insufficient evidence to either support or refute the routine use of mass, selective or opportunistic screening compared to no screening for reducing prostate cancer mortality, and no robust evidence is available regarding the impact of screening on quality of life, harms of screening, or its economic value.
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Longitudinal evaluation of prostate-specific antigen levels in men with and without prostate disease.

TL;DR: The most significant factor affecting serum PSA levels with age is the development of prostate disease, and rate of change in PSALevels may be a sensitive and specific early clinical marker for theDevelopment of prostate cancer.
References
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Exploratory data analysis

F. N. David, +1 more
- 01 Dec 1977 - 
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Exploratory Data Analysis.

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Procedures for Detecting Outlying Observations in Samples

TL;DR: In this paper, a procedure for determining statistically whether the highest observation, lowest observation, highest and lowest observations, or more of the observations in the sample are statistical outliers is given.
Journal Article

Origin and evolution of benign prostatic enlargement.

TL;DR: Quantitative analysis was applied to BPH development in 63 autopsy prostates, finding that BPH evolved through three processes: early diffuse gland growth, small nodule proliferation, and later nodule enlargement.
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