Journal ArticleDOI
The genetic control of meiosis.
Bruce S. Baker,Adelaide T. C. Carpenter,Michael S. Esposito,Rochelle Easton Esposito,L. Sandler +4 more
TLDR
This work has shown that mutants with altered meiotic exchange with defective mating-type control of sporulation have an important effect on fertility and this work aims to clarify these effects.Abstract:Â
CONTENTS INTRODUCTION ... ..... ... .. 54 Cross-Specific Comparisons 55 LOWER EUCARYOTES .... 57 Criteria for Mutant Isolation 57 Fertility 57 Effects on specific meiotic events 58 Mitotic disturbances 58 Yeasts 59 Fertility mutants ........ ... ... 60 Mutants with altered meiotic exchange .. ...... 62 Defective mating-type control of sporulation 63read more
Citations
More filters
Book ChapterDOI
Tetraploidy and the Evolution of Salmonid Fishes
TL;DR: It is proposed that genome doubling has taken place at least once in the evolution of vertebrates and isozyme studies that are consistent with this idea are described.
Journal ArticleDOI
Nondisjunction Mutants of the Nematode CAENORHABDITIS ELEGANS.
TL;DR: The frequency of males among the self progeny of wild-type Caenorhabditis elegans hermaphrodites (5AA; XX) is about one in 500, and fifteen him mutations have been identified that increase this frequency by a factor of ten to 150, as a result of increased X-chromosome nondisjunction.
Journal ArticleDOI
Meiotic chromosomes: it takes two to tango
TL;DR: This article reviews the current knowledge of the processes and structures that promote and maintain interactions between homologs and thereby ensure proper reductional chromosome segregation and places emphasis on observations made in recent years.
Journal ArticleDOI
Why Sex and Recombination
TL;DR: The effect of sex and recombination in breaking down negative correlations between favorable variants at different genetic loci, which increases the efficiency of natural selection, is likely to be a major factor favoring their evolution and maintenance.
Journal ArticleDOI
Repair of strand breaks by homologous recombination.
Maria Jasin,Rodney Rothstein +1 more
TL;DR: The enzymology of the process is discussed, followed by studies on DSB repair in living cells, and a historical context for the current view of HR is provided and how DSBs are processed during HR as well as interactions with other D SB repair pathways are described.
References
More filters
Journal ArticleDOI
A Manyfold Increase in Sister Chromatid Exchanges in Bloom's Syndrome Lymphocytes
TL;DR: It is postulate that the increase in the frequency of exchanges between nonsister-but-homologous chromatids and those between sister Chromatids in Bloom's syndrome represents aspects of one and the same disturbance.
Journal ArticleDOI
Xeroderma pigmentosum: biochemical and genetic characteristics.
James E. Cleaver,Dirk Bootsma +1 more
TL;DR: Clinical features of xeroderma pigmentosum; karyotype; cell killing and host cell reactivation after irradiation or exposure to chemical carcinogens ; biochemical defects in the common and de Sanctis-Cacchione forms of xERoderma pigments; cell hybridization and complementation groups.
Journal ArticleDOI
Chromosomal breakage in a rare and probably genetically determined syndrome of man.
TL;DR: A high frequency of chromosomal breakage and rearrangement has been found in cultured blood cells from six of seven individuals with a rare syndrome characterized by congenital telangiectatic erythema and stunted growth.
Journal ArticleDOI
Induction by alkylating agents of sister chromatid exchanges and chromatid breaks in Fanconi's anemia.
TL;DR: The results suggest that chromosomal breaks and rearrangements in Fanconi's anemia lymphocytes may result from a defect in a form of repair of DNA damage.
Journal ArticleDOI
Probable assignment of the Duffy blood group locus to chromosome 1 in man.
TL;DR: Evidence is presented that the Duffy blood group locus Fy, already believed to be linked to a congenital cataract locus4 Cae, is close to this uncoiler element Un, and that all three are probably on chromosome no. 1.