The Hair Follicle as a Dynamic Miniorgan
TLDR
In this review, basic concepts of hair follicle biology are presented and important recent advances in the field are summarized.About:
This article is published in Current Biology.The article was published on 2009-02-10 and is currently open access. It has received 798 citations till now. The article focuses on the topics: Hair follicle morphogenesis & Hair follicle.read more
Citations
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Epidemiology, diagnosis and management of hirsutism: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society
Héctor F. Escobar-Morreale,Enrico Carmina,Didier Dewailly,Alessandra Gambineri,Fahrettin Kelestimur,Paolo Moghetti,Michel Pugeat,Jie Qiao,Chandrika N Wijeyaratne,Selma F. Witchel,Robert J. Norman +10 more
TL;DR: Evidence-based diagnostic and treatment strategies that address not only the amelioration of hirsutism but also the treatment of the underlying etiology is essential for the proper management of affected women, especially considering that hirsUTism is, in most cases, a chronic disorder needing long-term follow-up.
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EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair
TL;DR: Conditionally target H3K27 methyltransferases Ezh2 and Ezh1 to address their roles in mouse skin homeostasis and reveal new insights into Polycomb-dependent tissue control, and provide a new twist to how different progenitors within one tissue respond to loss of H3k27me3.
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Hair follicle dermal papilla cells at a glance.
TL;DR: Mammalian skin is a highly tractable tissue in which to explore epithelial–mesenchymal interactions during development and in postnatal life and one population of these interactions is studied.
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The skin-resident and migratory immune system in steady state and memory: innate lymphocytes, dendritic cells and T cells.
TL;DR: Many of the innate and adaptive immune cell types associated with the skin are outlined, focusing on the steady state in mice and men, and include a broad update of dendritic cell function and T cell surveillance.
References
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Book
Fitzpatrick's Dermatology In General Medicine
Lowell A. Goldsmith,Thomas B. Fitzpatrick,Stephen I. Katz,Barbara A. Gilchrest,Amy S. Paller,David J. Leffell,K Wolff +6 more
TL;DR: Widely acclaimed dermatological treatise is completely revised and updated with over forty new chapters and an entirely new section on dermatologic surgery.
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Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
TL;DR: It is suggested that follicular stem cells reside in the bulge region, instead of the lower bulb, which provides insights into hair cycle control and the possible involvement of hair follicle stem cells in skin carcinogenesis.
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Defining the epithelial stem cell niche in skin.
Tudorita Tumbar,Géraldine Guasch,Valentina Greco,Cédric Blanpain,William E. Lowry,Michael Rendl,Elaine Fuchs +6 more
TL;DR: It is found that these cells rarely divide within their niche but change properties abruptly when stimulated to exit, and their transcriptional profile is determined, which, when compared to progeny and other SCs, defines the niche.
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Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche.
TL;DR: It is suggested that the niche microenvironment imposes intrinsic "stemness" features without restricting the establishment of epithelial polarity and changes in gene expression.
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Fitzpatrick's Dermatology in General Medicine
TL;DR: This completely revised and updated edition of ‘Fitzpatrick’ has further cemented its place in the practice of Dermatology with great clarity and easily ‘digestable’ reference material.