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Journal ArticleDOI

The healing of confined critical size cancellous defects in the presence of silk fibroin hydrogel

TLDR
In vitro and in vivo behaviour of an injectable silk fibroin (SF) hydrogel was studied through osteoblast cultures and after implantation in critical-size defects of rabbit distal femurs, confirming that SF hydrogels accelerated remodelling processes.
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This article is published in Biomaterials.The article was published on 2005-06-01. It has received 271 citations till now. The article focuses on the topics: Bone healing & Osteoblast.

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Silk as a biomaterial

TL;DR: Silks are fibrous proteins with remarkable mechanical properties produced in fiber form by silkworms and spiders that are biocompatible when studied in vitro and in vivo.
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Natural–origin polymers as carriers and scaffolds for biomolecules and cell delivery in tissue engineering applications

TL;DR: A wide range of natural-origin polymers with special focus on proteins and polysaccharides that are being used in research, or might be potentially useful as carriers systems for active biomolecules or as cell carriers with application in the tissue engineering field targeting several biological tissues are overviewed.
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Elastomeric biomaterials for tissue engineering

TL;DR: This article provides a comprehensive review on the elastomeric biomaterials used in tissue engineering, with emphasis on the most important candidates to date.
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Silk fibroin biomaterials for tissue regenerations.

TL;DR: The present article discusses the processing of silk fibroin into different forms of biomaterials followed by their uses in regeneration of different tissues.
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Stem cell-based tissue engineering with silk biomaterials.

TL;DR: Stem cell-based tissue engineering using 3D silk fibroin scaffolds has expanded the use of silk-based biomaterials as promising scaffolds for engineering a range of skeletal tissues like bone, ligament, and cartilage, as well as connective tissues like skin.
References
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Journal ArticleDOI

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

TL;DR: A committee of the Society to develop a unified system of termnology, suitable for adoption by the Journal of Bone and Mineral Research as part of its Instructions to Authors is formed, and is as complex and conceptually difficult as the field with which it deals.
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Silk-based biomaterials

TL;DR: Studies with well-defined silkworm silk fibers and films suggest that the core silk fibroin fibers exhibit comparable biocompatibility in vitro and in vivo with other commonly used biomaterials such as polylactic acid and collagen.
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Osteoinduction, osteoconduction and osseointegration.

TL;DR: Osseointegration is the stable anchorage of an implant achieved by direct bone-to-implant contact in craniofacial implantology and this mode of anchorage is the only one for which high success rates have been reported.
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Electrospinning of silk fibroin nanofibers and its effect on the adhesion and spreading of normal human keratinocytes and fibroblasts in vitro

TL;DR: The results indicate that the silk fibroin (SF) nanofibers may be a good candidate for the biomedical applications, such as wound dressing and scaffolds for tissue engineering.
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