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Journal ArticleDOI

The international registry on hand and composite tissue transplantation

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TLDR
Hand transplantation is feasible with a high success rate and satisfactory functional outcome, and patients developed protective sensibility, 90% of them developed tactile sensibility and 72% also a discriminative sensibility.
Abstract
The first hand transplantation was performed in Lyon, France, on 23 September 1998 by an international team of surgeons [1]. Since then, hand transplantation programmes have been launched in the United States, Austria, China, Italy, Belgium and Poland [2, 3, 4, 5, 6], and the teams felt the need to create a worldwide registry to provide a basis for cooperation and to share their experiences (Fig. 1). Since May 2002, all groups [7] performing hand transplantations have supplied detailed information to the International Registry on Hand and Composite Tissue Transplantation (IRHCTT; www.handregistry.com). Follow-up period ranged from 2 to 85 months (Table 1). A good number of composite tissue transplantations other than the hand have been performed around the world in the period 1994–2006, including the femoral diaphysis, the knee, the larynx, the uterus, the abdominal wall, a lower limb in conjoined twins, and most recently, the face in two centres.

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Book ChapterDOI

Chapter 8 Current Techniques and Concepts in Peripheral Nerve Repair

TL;DR: The currently available surgical treatment options for different types of nerve injuries in clinical conditions are reviewed and future directions in peripheral nerve reconstruction including, tolerance induction and minimal immunosuppression for nerve allografting, cell based supportive therapies and bioengineering of nerve conduits are reviewed.
Journal ArticleDOI

Facial transplantation: the first 9 years

TL;DR: Although episodes of acute skin rejection continue to pose a serious threat to face transplant recipients, all cases have been controlled with conventional immunosuppressive regimens, and no cases of chronic rejection have been reported.
Journal ArticleDOI

Feasibility, reproducibility, risks and benefits of face transplantation: a prospective study of outcomes.

TL;DR: Face transplantation has been reproducible under conventional immunosuppression and major improvements in facial aesthetic and function allowed patients to recover social relations and improved their quality of life.
References
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Journal ArticleDOI

The disabilities of the arm, shoulder and hand (DASH) outcome questionnaire: longitudinal construct validity and measuring self-rated health change after surgery

TL;DR: The DASH can detect and differentiate small and large changes of disability over time after surgery in patients with upper-extremity musculoskeletal disorders and show treatment effectiveness after surgery for subacromial impingement and carpal tunnel syndrome.
Journal ArticleDOI

Human hand allograft: report on first 6 months

TL;DR: If no further episode of rejection occurs, the functional prognosis of this graft should be similar to if not better than that reported in large series of autoreconstruction.

One-year follow-up

TL;DR: The “‘bladder-conscious” patient can protect and preserve bladder function but these bludders appear to remain vulnerable to infection and overdistention, perhaps permanently.
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