Journal ArticleDOI
The international registry on hand and composite tissue transplantation
Palmina Petruzzo,Marco Lanzetta,Jean-Michel Dubernard,Luis Landin,P. Cavadas,Raimund Margreiter,S. Schneeberger,Warren W. Breidenbach,Christina C. Kaufman,Jerzy Jablecki,Frederic Schuind,Christian C. Dumontier +11 more
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TLDR
Hand transplantation is feasible with a high success rate and satisfactory functional outcome, and patients developed protective sensibility, 90% of them developed tactile sensibility and 72% also a discriminative sensibility.Abstract:
The first hand transplantation was performed in Lyon, France, on 23 September 1998 by an international team of surgeons [1]. Since then, hand transplantation programmes have been launched in the United States, Austria, China, Italy, Belgium and Poland [2, 3, 4, 5, 6], and the teams felt the need to create a worldwide registry to provide a basis for cooperation and to share their experiences (Fig. 1). Since May 2002, all groups [7] performing hand transplantations have supplied detailed information to the International Registry on Hand and Composite Tissue Transplantation (IRHCTT; www.handregistry.com). Follow-up period ranged from 2 to 85 months (Table 1). A good number of composite tissue transplantations other than the hand have been performed around the world in the period 1994–2006, including the femoral diaphysis, the knee, the larynx, the uterus, the abdominal wall, a lower limb in conjoined twins, and most recently, the face in two centres.read more
Citations
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Journal ArticleDOI
The Banff 2007 working classification of skin-containing composite tissue allograft pathology.
Linda C. Cendales,Jean Kanitakis,Stefan Schneeberger,Stefan Schneeberger,Carolyn Burns,Philip Ruiz,Luis Landin,Myriam Remmelink,Charles W. Hewitt,T. Landgren,B. Lyons,Cinthia B. Drachenberg,Kim Solez,Allan D. Kirk,David E. Kleiner,Lorraine C. Racusen +15 more
TL;DR: A working classification is proposed, the Banff CTA‐07, for the categorization of CTA rejection, derived from a consensus discussion session attended by the first authors of three published classification systems, pathologists and researchers from international centers where clinical CTA has been performed.
Book ChapterDOI
Chapter 8 Current Techniques and Concepts in Peripheral Nerve Repair
TL;DR: The currently available surgical treatment options for different types of nerve injuries in clinical conditions are reviewed and future directions in peripheral nerve reconstruction including, tolerance induction and minimal immunosuppression for nerve allografting, cell based supportive therapies and bioengineering of nerve conduits are reviewed.
Journal ArticleDOI
First clinical uterus transplantation trial: a six-month report
Mats Brännström,Liza Johannesson,Pernilla Dahm-Kähler,Anders Enskog,Johan Mölne,Niclas Kvarnström,Cesar Diaz-Garcia,Ashraf Hanafy,Cecilia Lundmark,Janusz Marcickiewicz,Markus Gäbel,Klaus Groth,Randa Akouri,Saskia Eklind,Jan Holgersson,Andreas Tzakis,Michael Olausson +16 more
TL;DR: The results demonstrate the feasibility of live-donor UTx with a low-dose immunosuppressive protocol, and this type of transplantation may become a treatment of absolute uterine-factor infertility (AUFI).
Journal ArticleDOI
Facial transplantation: the first 9 years
Saami Khalifian,Saami Khalifian,Philip S. Brazio,Raja Mohan,Cynthia K. Shaffer,Gerald Brandacher,Rolf N. Barth,Eduardo D. Rodriguez +7 more
TL;DR: Although episodes of acute skin rejection continue to pose a serious threat to face transplant recipients, all cases have been controlled with conventional immunosuppressive regimens, and no cases of chronic rejection have been reported.
Journal ArticleDOI
Feasibility, reproducibility, risks and benefits of face transplantation: a prospective study of outcomes.
Laurent Lantieri,Mikael Hivelin,Vincent Audard,Marc-David Benjoar,Jean-Paul Meningaud,Frank Bellivier,Nicolas Ortonne,Jean-Pascal Lefaucheur,A. Gilton,C. Suberbielle,Jean Marty,Peter Lang,Philippe Grimbert +12 more
TL;DR: Face transplantation has been reproducible under conventional immunosuppression and major improvements in facial aesthetic and function allowed patients to recover social relations and improved their quality of life.
References
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Journal ArticleDOI
The disabilities of the arm, shoulder and hand (DASH) outcome questionnaire: longitudinal construct validity and measuring self-rated health change after surgery
TL;DR: The DASH can detect and differentiate small and large changes of disability over time after surgery in patients with upper-extremity musculoskeletal disorders and show treatment effectiveness after surgery for subacromial impingement and carpal tunnel syndrome.
Journal ArticleDOI
Human hand allograft: report on first 6 months
Jean-Michel Dubernard,Earl Owen,Guillaume Herzberg,Marco Lanzetta,Xavier Martin,H. Kapila,M. Dawahra,Nadey S Hakim +7 more
TL;DR: If no further episode of rejection occurs, the functional prognosis of this graft should be similar to if not better than that reported in large series of autoreconstruction.
One-year follow-up
TL;DR: The “‘bladder-conscious” patient can protect and preserve bladder function but these bludders appear to remain vulnerable to infection and overdistention, perhaps permanently.
Journal ArticleDOI
Outcomes 18 Months after the First Human Partial Face Transplantation
Jean-Michel Dubernard,Benoît Lengelé,Emmanuel Morelon,Sylvie Testelin,Lionel Badet,C. Moure,Jean-Luc Beziat,Stéphanie Dakpé,Jean Kanitakis,Cédric D'Hauthuille,Assia El Jaafari,Palmina Petruzzo,Nicole Lefrançois,Farid Taha,Angela Sirigu,Giovanni Di Marco,Esther Carmi,Danielle Bachmann,Sophie Cremades,Pascal Giraux,Gabriel Burloux,Olivier Hequet,Nathalie Parquet,Camille Francès,Mauricette Michallet,Xavier Martin,Bernard Devauchelle +26 more
TL;DR: In this patient who underwent the first partial face transplantation, the functional and aesthetic results 18 months after transplantation are satisfactory.
Journal ArticleDOI
The Banff 2007 working classification of skin-containing composite tissue allograft pathology.
Linda C. Cendales,Jean Kanitakis,Stefan Schneeberger,Stefan Schneeberger,Carolyn Burns,Philip Ruiz,Luis Landin,Myriam Remmelink,Charles W. Hewitt,T. Landgren,B. Lyons,Cinthia B. Drachenberg,Kim Solez,Allan D. Kirk,David E. Kleiner,Lorraine C. Racusen +15 more
TL;DR: A working classification is proposed, the Banff CTA‐07, for the categorization of CTA rejection, derived from a consensus discussion session attended by the first authors of three published classification systems, pathologists and researchers from international centers where clinical CTA has been performed.