Journal ArticleDOI
The Interval between Pregnancies and the Risk of Preeclampsia
TLDR
The protective effect of previous pregnancy against preeclampsia is transient and after adjustment for the interval between births, a change of partner is not associated with an increased risk of preeClampsia.Abstract:
Background The risk of preeclampsia is generally lower in second pregnancies than in first pregnancies, but not if the mother has a new partner for the second pregnancy. One explanation is that the...read more
Citations
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Journal ArticleDOI
Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies
TL;DR: Factors that may be present at antenatal booking and the underlying evidence base can be used to assess risk at booking so that a suitable surveillance routine to detect pre-eclampsia can be planned for the rest of the pregnancy.
Journal ArticleDOI
The classification, diagnosis and management of the hypertensive disorders of pregnancy: A revised statement from the ISSHP.
Andrea L. Tranquilli,Gustaaf A. Dekker,Laura A. Magee,James S. Roberts,Bahaeddine M Sibai,W. Steyn,Gerda G. Zeeman,Mark Brown +7 more
TL;DR: The purpose of this document is to update ISSHP thinking on this subject and recommend that a broad definition, at times not including proteinuria, could be applied for the clinical definition of pre-eclampsia whilst the inclusion of proteinuria would ensure more specificity around the diagnosis when reporting clinical criteria for patients enrolled in scientific research.
Journal ArticleDOI
Hypertensive Disorders of Pregnancy: ISSHP Classification, Diagnosis, and Management Recommendations for International Practice.
Mark Brown,Laura A. Magee,Louise C. Kenny,S. Ananth Karumanchi,Fergus P. McCarthy,Shigeru Saito,David Hall,Charlotte E. Warren,Gloria Adoyi,Salisu Mohammed Ishaku +9 more
TL;DR: The cause(s) of preeclampsia and the optimal clinical management of the hypertensive disorders of pregnancy remain uncertain; therefore, it is recommended that every hypertensive pregnant woman be offered an opportunity to participate in research, clinical trials, and follow-up studies.
Journal ArticleDOI
Defining “Highly Qualified Teachers”: What Does “Scientifically-Based Research” Actually Tell Us?
TL;DR: A recent analysis by Rivkin, Hanushek, and Kain this paper found that student achievement gains are much more influenced by a student's assigned teacher than other factors like class size and class composition.
Journal ArticleDOI
Predictive Value of the sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia
Harald Zeisler,Elisa Llurba,Frédéric Chantraine,Manu Vatish,Anne Cathrine Staff,Maria Sennström,Matts Olovsson,Shaun P. Brennecke,Holger Stepan,Deirdre Allegranza,Peter Dilba,Maria Schoedl,Martin Hund,Stefan Verlohren +13 more
TL;DR: An sFlt-1:PlGF ratio of 38 or lower can be used to predict the short-term absence of preeclampsia in women in whom the syndrome is suspected clinically.
References
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Journal ArticleDOI
Pathogenesis and genetics of pre-eclampsia.
James M. Roberts,D. W. Cooper +1 more
TL;DR: There are genetic components to susceptibility, but the relative contributions of maternal and fetal genotypes are still unclear and whole-genome mapping could ultimately define the causative genes.
Journal ArticleDOI
Etiology and pathogenesis of preeclampsia: Current concepts
Gustaaf A. Dekker,Baha M. Sibai +1 more
TL;DR: The possibility of genetic imprinting should be considered in future genetic investigations of preeclampsia, as it is likely to reduce albumin’s antitoxic activity to a point at which very-low density lipoprotein toxicity is expressed.
Journal ArticleDOI
Effect of the interval between pregnancies on perinatal outcomes.
TL;DR: The optimal interpregnancy interval for preventing adverse perinatal outcomes is 18 to 23 months, and shorter and longer interp pregnancy intervals were associated with higher risks.
Journal ArticleDOI
Risk factors associated with preeclampsia in healthy nulliparous women
Bahaeddine M Sibai,M. Ewell,R. J. Levine,Mark A. Klebanoff,J. Esterlitz,Patrick M. Catalano,Robert L. Goldenberg,G. Joffe +7 more
TL;DR: These risk factors initially found to be significant were body mass index, systolic blood pressure, diastolicBlood pressure, non-white race (African-American and other), clinical center, and smoking and should aid in understanding the pathophysiologic characteristics of this syndrome.
Journal ArticleDOI
Fetal and maternal contributions to risk of pre-eclampsia: population based study
Rolv T. Lie,Svein Rasmussen,Helge Brunborg,Håkon K. Gjessing,Erik Lie-Nielsen,Lorentz M. Irgens +5 more
TL;DR: Both the mother and the fetus contribute to the risk of pre-eclampsia, the contribution of the fetus being affected by paternal genes, and search for specific genes that predispose for pre- eClampsia should include the fetus as well as the mother.