Journal ArticleDOI
The nature of retinoblastoma. II. Photoreceptor differentiation: an electron microscopic study.
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TLDR
In this histopathologic study of retinoblastomas exhibiting an unusual form of dif ferentiation, it seemed apparent that these tumors were producing structures resem bling elements of the photoreceptor cell.About:
This article is published in American Journal of Ophthalmology.The article was published on 1970-03-01. It has received 129 citations till now. The article focuses on the topics: Photoreceptor cell.read more
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Journal Article
Transplantation of Y79 cells into rat eyes: an in vivo model of human retinoblastomas.
M. del Cerro,Gail M. Seigel,Eliot Lazar,Donald A. Grover,C. del Cerro,D H Brooks,David A. DiLoreto,G Chader +7 more
TL;DR: After intraretinal xenografting, human Y79 retinoblastoma cells retain a highly tumoral nature despite many years of in vitro propagation.
Journal ArticleDOI
L1 increases adhesion-mediated proliferation and chemoresistance of retinoblastoma
Dong Hyun Jo,Dong Hyun Jo,Dong Hyun Jo,Kyungmin Lee,Kyungmin Lee,Jin Hyoung Kim,Jin Hyoung Kim,Hyoung Oh Jun,Hyoung Oh Jun,Young Hoon Kim,Young Lai Cho,Young Suk Yu,Young Suk Yu,Jeong Ki Min,Jeong Ki Min,Jeong Hun Kim +15 more
TL;DR: Targeted therapy to L1 might be effective in the treatment of retinoblastoma tumors, especially which rapidly proliferate and demonstrate resistance to conventional chemotherapeutic drugs.
Journal ArticleDOI
The TAg-RB Murine Retinoblastoma Cell of Origin Has Immunohistochemical Features of Differentiated Müller Glia with Progenitor Properties
Sanja Pajovic,Timothy W. Corson,Clarellen Spencer,Helen Dimaras,Helen Dimaras,M Orlic-Milacic,M Orlic-Milacic,Mellone N. Marchong,Mellone N. Marchong,Mellone N. Marchong,Kwong Him To,Kwong Him To,Brigitte L. Thériault,Mark Auspitz,Brenda L. Gallie +14 more
TL;DR: TAg-RB tumors displayed molecular similarity to human retinoblastoma and origin in a cell with features of differentiated Müller glia with progenitor properties, supporting preclinical evidence that this model is useful for comparative studies between mouse and human.
Journal Article
Histopathologic Grading of Anaplasia for Retinoblastoma
Pia R. Mendoza,G. Baker Hubbard,Jill R. Wells,Charles S. Specht,Qing Zhang,Hans E. Grossniklaus +5 more
Journal ArticleDOI
AP2 transcription factor induces apoptosis in retinoblastoma cells.
TL;DR: TFAP2A and TFAP2B, which map to chromosome arm 6p, are expressed in the amacrine and horizontal cells of human retina and it is proposed that inability to differentiate along the amACrine/horizontal cell lineages may underlie retinoblastoma tumor formation.
References
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Book ChapterDOI
Cilia and Flagella
TL;DR: Cilia are motile, hairlike appendages on the free surface of cells that play an important role in such diverse physiological processes as locomotion, alimentation, circulation, respiration, reproduction, and sensory reception.
Journal ArticleDOI
The Nature of Retinoblastoma. I. Photoreceptor Differentiation: A Clinical and Histopathologic Study
Journal Article
Applications of histochemical methods for the demonstration of acid mucopolysaccharides to ophthalmic pathology.
Journal ArticleDOI
Beiträge zur Histogenese und Histologie der Netzhaut, des Pigmentepithels und des Sehnerven
TL;DR: In this paper, the authors present an overview of the evolution of the Retinazelle and its relationship with the rest of the body of work in the field of physicologischen excavations.