The Pharmacological Effects of Fagonia cretica linn Ethanolic Extract on Isolated Rabbit Intestine
Aimun Ae. Ahmed,Mawahib E. H. Elfeil,Samrin K. N. Ahmed,Tasnim O. Elsammani +3 more
- Vol. 1, Iss: 2, pp 91-98
TLDR
Results revealed that Fagonia cretica exhibited a dose-dependent relaxant activity on rabbit intestine similar to that produced by standard adrenaline with, Emax, EC50 and EC50 as mean ± S.E.M, and compared statistically.Abstract:
The aim of this study was to verify the pharmacological effect(s) of the Fagonia cretica linn (Zygophyllaceae) ethanolic extract and to determine the mechanism(s) underlay its action using isolated rabbit intestine. The cumulative dose-response curves of the Fagonia cretica extract and standard adrenaline were constructed using different doses ranged (10 -3 - 10 2 µg/ml), and (10 -9 - 10 -5 M) alone, and in the presence of a single dose of a blocker, then the values of EC50, Emax and pA2 were determined as mean ± S.E.M, and compared statistically. The adrenergic non-selective blockers, phentolamine and propranolol in concentrations of (10 -8 and 10 -5 M) were used to elucidate the exact mechanism mediating the relaxant effect of the ethanolic extract of Fagonia cretica linn. Results revealed that Fagonia cretica exhibited a dose-dependent relaxant activity on rabbit intestine similar to that produced by standard adrenaline with, Emax= [56.4 ± 7.5], [7.2 ± 4.3] and EC50= [0.12 ± 0.27], [9.85 ± 1.6] x 10 -6read more
Citations
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Chemical composition and medicinal significance of Fagonia cretica: a review
TL;DR: Fagonia cretica Linn.
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Antibacterial efficacy of silver nanoparticles prepared using Fagonia cretica L. leaf extract
TL;DR: It was concluded that the AgNP prepared from F. cretica extract were spherical and aggregated and were found effective against different clinical isolates of bacteria.
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The species of genus fagonia in Libya: (A comprehensive review)
Abdullah Alamami,Fatma Elshibani,Naema Elremali,Areej Almaktouf Daboub,Samar Ben Zaed,Mohamed M. M. Bumadian +5 more
TL;DR: This review study has gathered the important research that has been carried out on the species that grow in Libya and includes an exhaustive survey of literature about the medicinal value and the bioactivities of various extracts obtained from these Fagonia species using references from major databases.
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In-depth in-vitro and in-vivo anti-diabetic evaluations of Fagonia cretica mediated biosynthesized selenium nanoparticles.
Haider A. Khan,Mehreen Ghufran,Sulaiman Shams,Al B B Jamal,Muhammad Ayaz,Mehran Ullah,Abbas Khan,Mohammad Imran Khan,Zuhier Awan +8 more
TL;DR: In this paper , the anti-diabetic potentials of Fagonia cretica mediated biogenic selenium nanoparticles (FcSeNPs) using in-vitro and invivo approaches were assessed.
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Comparative evaluation of biomedical and phytochemical applications of zinc nanoparticles by using Fagonia cretica extracts
Bushra Hafeez Kiani,Fizza Ikram,Huma Fatima,Aiyeshah Alhodaib,Ihsan-ul Haq,Tofeeq Ur-Rehman,Iffat Naz +6 more
TL;DR: In this article , the authors used Fagonia cretica extracts to formulate Zinc oxide nanoparticles (ZnO NPs) by using four different solvents; methanol (MeOH), n-hexane (n-Hexane), aqueous (Aq), and ethyl acetate (EA).
References
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Phylogenetic relationships and biogeography of the desert plant genus Fagonia (Zygophyllaceae), inferred by parsimony and Bayesian model averaging.
TL;DR: Phylogenetic relationships within Fagonia were inferred from analyses of plastid trnL intron and nuclear ribosomal ITS DNA sequences, and Vicariance-dispersal analysis indicated that the occurrences of Fagonian species in South America and southern Africa are due to dispersals, and also, that the ancestor ofFagonia had a distribution compatible with the boreotropics hypothesis.
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Antihaemorrhagic potentials of Fagonia cretica against Naja naja karachiensis (black Pakistan cobra) venom.
Muhammad Tahir Razi,Muhammad Hassham Hassan Bin Asad,Taous Khan,Muhammad Zabta Chaudhary,Muhammad Tayyab Ansari,Muhammad Anwar Arshad,Qazi Najam us Saqib +6 more
TL;DR: The extract effectively eliminated and neutralised, in a dose-dependent manner, the haemorrhagic activity of snake venom and provides a scientific base for the use of F. cretica in traditional medicine for the treatment of snake bite.
Journal ArticleDOI
Effect of Ardhabilva Kvatha Curna - an Ayurvedic formulation on lipid profile after chronic administration.
TL;DR: The present study reveals that Ardhabilva Kvatha Curna possesses hypotriglyceridemic property, and the change in the lipid profile both in the male and female rats was in the same trend except Very Low Density Lipoprotein.