The synthesis of choline plasmalogen by the methylation pathway in rat brain
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TLDR
Experimental data are reported which indicate the direct transfer of methyl groups from labelled S-adenosyl-L-methionine into ethanolamine plasmalogen, thus indicating a possible pathway for choline plAsmalogen synthesis both in whole brain homogenate and in brain microsomes in vitro.About:
This article is published in FEBS Letters.The article was published on 1981-08-17 and is currently open access. It has received 29 citations till now. The article focuses on the topics: Methylation.read more
Citations
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Lipids of nervous tissue: composition and metabolism.
TL;DR: The period of discovery of new lipids in the nervous system appears to be over and all the major lipid components have been discovered and a great deal is now known about their structure and metabolism.
Journal ArticleDOI
Choline and cholinergic neurons.
TL;DR: Brain choline concentrations are generally higher than plasma concentrations, but depend on plasma concentrations because of the kinetic characteristics of the blood-brain-barrier transport system.
Journal ArticleDOI
Brain docosahexaenoic acid uptake and metabolism
TL;DR: A comprehensive overview of brain DHA metabolism is provided, encompassing many of the pathways and key enzymatic regulators governingbrain DHA uptake and metabolism, and focuses on the release of non-esterified DHA and subsequent production of bioactive mediators and the evidence of their proposed activity within the brain.
Journal ArticleDOI
Metabolism and functions of phosphatidylserine in mammalian brain.
TL;DR: Several aspects of brain PtdSer metabolism and functions seem related to the high polyunsaturated fatty acids content, particularly docosahexaenoic acid (DHA).
Prostaglandins, Leukotrienes and Essential Fatty Acids
Gunveen Kaur,Andrew J. Sinclair,David Cameron-Smith,Daniel P. Barr,Juan C. Molero-Navajas,Nicky Konstantopoulos +5 more
TL;DR: It is suggested that the presence of 20:3n-9 in cartilage may be related to its vesselfree status and that it may be useful for the treatment of disorders with excessive vasculature.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Lipid extraction of tissues with a low-toxicity solvent
Atsushi Hara,Norman S. Radin +1 more
TL;DR: An improved method for extracting the lipids from tissues consists of the use of hexane:isopropanol, followed by a wash of the extract with aqueous sodium sulfate to remove nonlipid contaminants.
Journal ArticleDOI
The alk-1-enyl group content of mammalian myelin phosphoglycerides by quantitative two-dimensional thin-layer chromatography.
TL;DR: Myelin phospholipids have been examined by a separation-reaction-separation procedure for two-dimensional thin-layer chromatography on silica gel and development in the second dimension quantitatively separates acid-labile and acid-stable phosphoglycerides as well as the aldehydes released from the acid- labile phosphoglycers.
Journal ArticleDOI
Base-exchange reactions for the synthesis of phospholipids in nervous tissue: the incorporation of serine and ethanolamine into the phospholipids of isolated brain microsomes.
TL;DR: The incorporation of serine and ethanolamine was actively inhibited by Hg2+, Co2+, Cu2+ and Mn2+ ions, and was abolished by ethylenediamine tetra‐acetate treatment.
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