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Open AccessJournal ArticleDOI

The What and How of prefrontal cortical organization

Randall C. O'Reilly
- 01 Aug 2010 - 
- Vol. 33, Iss: 8, pp 355-361
TLDR
There is indeed a systematic organization across PFC areas, with an important functional distinction between ventral and dorsal regions characterized as processing What versus How information, respectively, and this distinction has implications for the rostro-caudal and medial-lateral axes of organization.
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This article is published in Trends in Neurosciences.The article was published on 2010-08-01 and is currently open access. It has received 255 citations till now. The article focuses on the topics: Prefrontal cortex.

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Functional network organization of the human brain

TL;DR: In this article, the authors studied functional brain organization in healthy adults using resting state functional connectivity MRI and proposed two novel brain wide graphs, one of 264 putative functional areas, the other a modification of voxelwise networks that eliminates potentially artificial short-distance relationships.
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The Expected Value of Control: An Integrative Theory of Anterior Cingulate Cortex Function

TL;DR: This work presents a normative model of EVC that integrates three critical factors: the expected payoff from a controlled process, the amount of control that must be invested to achieve that payoff, and the cost in terms of cognitive effort.
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Unity and diversity of executive functions: Individual differences as a window on cognitive structure.

TL;DR: It is highlighted how considering individual differences at the behavioral and neural levels can add considerable insight to the investigation of the functional organization of the brain, and some key points about individual differences to consider when interpreting neuropsychological patterns of dissociation are highlighted.
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The ventral visual pathway: an expanded neural framework for the processing of object quality

TL;DR: It is proposed that the ventral pathway is best understood as a recurrent occipitotemporal network containing neural representations of object quality both utilized and constrained by at least six distinct cortical and subcortical systems.
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Motivation and Cognitive Control: From Behavior to Neural Mechanism

TL;DR: It is argued that neuroscientific evidence plays a critical role in understanding the mechanisms by which motivation and cognitive control interact, and is advocated for a view of control function that treats it as a domain of reward-based decision making.
References
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Journal ArticleDOI

Control of goal-directed and stimulus-driven attention in the brain

TL;DR: Evidence for partially segregated networks of brain areas that carry out different attentional functions is reviewed, finding that one system is involved in preparing and applying goal-directed selection for stimuli and responses, and the other is specialized for the detection of behaviourally relevant stimuli.
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An integrative theory of prefrontal cortex function

TL;DR: It is proposed that cognitive control stems from the active maintenance of patterns of activity in the prefrontal cortex that represent goals and the means to achieve them, which provide bias signals to other brain structures whose net effect is to guide the flow of activity along neural pathways that establish the proper mappings between inputs, internal states, and outputs needed to perform a given task.
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Separate visual pathways for perception and action.

TL;DR: It is proposed that the ventral stream of projections from the striate cortex to the inferotemporal cortex plays the major role in the perceptual identification of objects, while the dorsal stream projecting from the stripping to the posterior parietal region mediates the required sensorimotor transformations for visually guided actions directed at such objects.
Journal ArticleDOI

Conflict monitoring and anterior cingulate cortex: an update

TL;DR: Recent research has begun to shed light on the larger function of the ACC, suggesting some new possibilities concerning how conflict monitoring might fit into the cingulate's overall role in cognition and action.
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