Journal ArticleDOI
Parallel Organization of Functionally Segregated Circuits Linking Basal Ganglia and Cortex
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TLDR
The basal ganglia serve primarily to integrate diverse inputs from the entire cerebral cortex and to "funnel" these influences, via the ventrolateral thalamus, to the motor cortex.Abstract:
Information about the basal ganglia has accumulated at a prodigious pace over the past decade, necessitating major revisions in our concepts of the structural and functional organization of these nuclei. From earlier data it had appeared that the basal ganglia served primarily to integrate diverse inputs from the entire cerebral cortex and to "funnel" these influences, via the ventrolateral thalamus, to the motor cortex (Allen & Tsukahara 1974, Evarts & Thach 1969, Kemp & Powell 1971). In particular, the basalread more
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An integrative theory of prefrontal cortex function
Earl K. Miller,Jonathan D. Cohen +1 more
TL;DR: It is proposed that cognitive control stems from the active maintenance of patterns of activity in the prefrontal cortex that represent goals and the means to achieve them, which provide bias signals to other brain structures whose net effect is to guide the flow of activity along neural pathways that establish the proper mappings between inputs, internal states, and outputs needed to perform a given task.
Journal ArticleDOI
The organization of the human cerebral cortex estimated by intrinsic functional connectivity
B.T. Thomas Yeo,Fenna M. Krienen,Jorge Sepulcre,Jorge Sepulcre,Mert R. Sabuncu,Mert R. Sabuncu,Danial Lashkari,Marisa O. Hollinshead,Marisa O. Hollinshead,Joshua L. Roffman,Jordan W. Smoller,Lilla Zöllei,Jonathan R. Polimeni,Bruce Fischl,Bruce Fischl,Hesheng Liu,Randy L. Buckner +16 more
TL;DR: In this paper, the organization of networks in the human cerebrum was explored using resting-state functional connectivity MRI data from 1,000 subjects and a clustering approach was employed to identify and replicate networks of functionally coupled regions across the cerebral cortex.
Journal ArticleDOI
The functional anatomy of basal ganglia disorders.
TL;DR: A model in which specific types of basal ganglia disorders are associated with changes in the function of subpopulations of striatal projection neurons is proposed, which suggests that the activity of sub Populations of Striatal projections neurons is differentially regulated by striatal afferents and that different striatal projections may mediate different aspects of motor control.
Journal ArticleDOI
Functional architecture of basal ganglia circuits: neural substrates of parallel processing
TL;DR: Recent evidence indicating that a parallel functional architecture may also be characteristic of the organization within each individual circuit is discussed, which represents a significant departure from earlier concepts of basal ganglia organization.
Journal ArticleDOI
Predictive Reward Signal of Dopamine Neurons
TL;DR: Dopamine systems may have two functions, the phasic transmission of reward information and the tonic enabling of postsynaptic neurons.
References
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Journal ArticleDOI
Efferent Connections and Nigral Afferents of the Nucleus Accumbens Septi in the Rat
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