Thermal independent silicon-nitride slot waveguide biosensor with high sensitivity.
Xiaoguang Tu,Junfeng Song,Tsung-Yang Liow,Mi Kyoung Park,Jessie Quah Yiying,Jack Sheng Kee,Mingbin Yu,Guo-Qiang Lo +7 more
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TLDR
A Mach-Zehnder Interferometer (MZI) biosensor based on silicon nitride slot waveguides is presented, designed for minimal temperature dependence without compromising the performance in terms of sensitivity and detection limit.Abstract:
As the sensitivity and detection limit of photonic refractive index (RI) biosensor increases, the temperature dependence becomes a major challenge. In this paper, we present a Mach-Zehnder Interferometer (MZI) biosensor based on silicon nitride slot waveguides. The biosensor is designed for minimal temperature dependence without compromising the performance in terms of sensitivity and detection limit. With air cladding, the measured surface sensitivity and detection limit of MZI biosensor reach 7.16 nm/ (ngmm−2) and 1.30 (pgmm−2), while achieving a low temperature dependence is 5.0 pm/o C. With water cladding, the measured bulk sensitivity and detection limit reach 1730(2π)/RIU and 1.29 × 10−5 RIU respectively. By utilizing Vernier effect through cascaded MZI structures, the measured sensitivity enhancement factor is 8.38, which results in a surface detection limit of 0.155 (pgmm−2).read more
Citations
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Journal ArticleDOI
Silicon Photonic Biosensors Using Label-Free Detection.
TL;DR: An overview of the state-of-the-art in evanescent field biosensing technologies including interferometer, microcavity, photonic crystal, and Bragg grating waveguide-based sensors, as well as real biomarkers for label-free detection are exhibited and compared.
Journal ArticleDOI
Highly sensitive Mach–Zehnder interferometer biosensor based on silicon nitride slot waveguide
Qing Liu,Xiaoguang Tu,Kyung Woo Kim,Jack Sheng Kee,Yong Shin,Kyungsup Han,Kyungsup Han,Yong-Jin Yoon,Guo-Qiang Lo,Mi Kyoung Park +9 more
TL;DR: In this article, a label-free Mach-Zehnder interferometer (MZI) biosensor based on a silicon nitride slot waveguide was proposed for the detection and quantification of the methylation of DAPK (deathassociated protein kinase ) gene.
Journal ArticleDOI
Label-free optical resonant sensors for biochemical applications
Caterina Ciminelli,C. M. Campanella,Francesco Dell'Olio,Carlo Edoardo Campanella,Mario Nicola Armenise +4 more
TL;DR: Resonant wavelength shift and the modal splitting occurring when the analyte interacts with microresonant structures are the two major physical aspects analyzed in this paper.
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Recent advances in integrated photonic sensors.
Vittorio M. N. Passaro,Corrado de Tullio,Benedetto Troia,Mario La Notte,Giovanni Giannoccaro,Francesco De Leonardis +5 more
TL;DR: Sensing principles commonly used in optical detection are presented, focusing on sensor performance features such as sensitivity, selectivity and rangeability, and recent developments in the field of photonic sensing are reviewed.
Journal ArticleDOI
Ultra-sensitive chip-based photonic temperature sensor using ring resonator structures.
TL;DR: It is shown that silicon-based optical ring resonator devices can resolve temperature differences of 1 mK using the traditional wavelength scanning methodology.
References
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