Journal ArticleDOI
Über aktivierte Ester. I. Aktivierte Ester der Hippursäure und ihre Umsetzungen mit Benzylamin
Reads0
Chats0
TLDR
In this article, a number of activated esters of hippuric acid are compared and the best acylating agent seems to be the cyanomethylester which is an easily accessible, cristalline, and stable compound, reacting easily with benzylamine at room temperature.Abstract:
Introduction of electron-attracting substituents into the alcoholic component of methyl-hippurate leads to activated esters which are characteristic acylating agents. A number of activated esters of hippuric acid are compared. The best acylating agent seems to be the cyanomethylester which is an easily accessible, cristalline, and stable compound, reacting easily with benzylamine at room temperature.read more
Citations
More filters
Book ChapterDOI
Preparation of Peptides and Ureas Using Reactive Amides or Imides
Stefan Goldschmidt,H. L. Krauss +1 more
TL;DR: A rational peptide synthesis must fulfill, in general, the following requirements: 1. Carefully controlled reaction conditions, in which particularly an attack on protective groups is avoided (1). 2. Retention of optical activity by introducing optically active amino acids. 3. High yields, which permit repetitive employment for building oligopeptides in a stepwise manner as discussed by the authors.
Journal ArticleDOI
Depsipeptides Communication 31. Synthesis of depsipeptides containing α-hydroxy α-amino acid residues
TL;DR: Depsipeptides containing α-hydroxy α-amino acid residues as hydroxy-acid component were synthesized and used as building blocks for new high-performance liquid chromatography apparatus.
Journal ArticleDOI
Über α‐Aminosäure‐2‐hydroxy‐cyclohexylamide
TL;DR: In this article, trans-2-hydroxycyclohexylamides of α-aminoacids, a new class of potential tridentate chelating agents, have been synthesized.
Journal ArticleDOI
Synthesen mit α-Halogenäthern†
TL;DR: The α-Halogenathers as mentioned in this paper have been untersucht seit longem in verschiedenen Arbeitskreisen unterstanden, das diese Verbindungsklasse auf Grund ihrer besonderen Reaktionsfahigkeit als praparative Hilfsmittel bzw als Zwischenprodukte fur eine ganze Reihe verschtwoener Synthesen eingesetzt werden.
References
More filters
Journal ArticleDOI
Über Peptidsynthesen. 8. Mitteilung Bildung von S‐haltigen Peptiden durch intramolekulare Wanderung von Aminoacylresten
Book ChapterDOI
The synthesis of peptides
TL;DR: This chapter focuses on the available methods for the synthesis of peptides and evaluates their relative difficulty, their adaptability to meet problems encountered in amino acid chemistry, and the yield and purity of the products of synthesis.
Journal ArticleDOI
Synthese von S‐Lactyl‐ und S‐β‐Oxybutyryl‐glutathionn
Theodor Wieland,Herbert Koppe +1 more
Journal ArticleDOI
Coenzym A: Modellreaktionen zur enzymatischen Aktivierung von Acylderivaten des Coenzyms A
Robert Schwyzer,Ch. Hürlimann +1 more
TL;DR: In this paper, the reactivity of esters of thiolcarboxylic acids with amino compounds is strongly and specifically enhanced by metal ions possessing affinity for the sulfur atom.