Journal ArticleDOI
Über aktivierte Ester. I. Aktivierte Ester der Hippursäure und ihre Umsetzungen mit Benzylamin
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TLDR
In this article, a number of activated esters of hippuric acid are compared and the best acylating agent seems to be the cyanomethylester which is an easily accessible, cristalline, and stable compound, reacting easily with benzylamine at room temperature.Abstract:
Introduction of electron-attracting substituents into the alcoholic component of methyl-hippurate leads to activated esters which are characteristic acylating agents. A number of activated esters of hippuric acid are compared. The best acylating agent seems to be the cyanomethylester which is an easily accessible, cristalline, and stable compound, reacting easily with benzylamine at room temperature.read more
Citations
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The α-Chymotrypsin-catalyzed Hydrolysis of α-N-Benzoyl-β-(4-pyridyl-1-oxide)-L-alanine Methyl Ester and of α-N-(Nicotinyl-1-oxide)-L-phenylalanine Methyl Ester1
Robert L. Bixler,Carl Niemann +1 more
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Active ester-based peptide bond formation and its application in peptide synthesis
TL;DR: In this article , the amide bond formed between α-amino acids constitutes the backbone of peptides and proteins and peptide bonds can be constructed efficiently under mild reaction conditions in nature.
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Gas chromatographic study of the reactivity of toluidines towards an active diester
TL;DR: In this article, the rate of reaction of o -, m - and p -toluidine with diphenyl sebacate was determined under plug-flow gas chromatographic conditions.
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Zur Kenntnis von N2‐substituierten Säurehydraziden
Th. Rinderspacher,Bernhard Prijs +1 more
References
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Journal ArticleDOI
Über Peptidsynthesen. 8. Mitteilung Bildung von S‐haltigen Peptiden durch intramolekulare Wanderung von Aminoacylresten
Book ChapterDOI
The synthesis of peptides
TL;DR: This chapter focuses on the available methods for the synthesis of peptides and evaluates their relative difficulty, their adaptability to meet problems encountered in amino acid chemistry, and the yield and purity of the products of synthesis.
Journal ArticleDOI
Synthese von S‐Lactyl‐ und S‐β‐Oxybutyryl‐glutathionn
Theodor Wieland,Herbert Koppe +1 more
Journal ArticleDOI
Coenzym A: Modellreaktionen zur enzymatischen Aktivierung von Acylderivaten des Coenzyms A
Robert Schwyzer,Ch. Hürlimann +1 more
TL;DR: In this paper, the reactivity of esters of thiolcarboxylic acids with amino compounds is strongly and specifically enhanced by metal ions possessing affinity for the sulfur atom.