Update on the Role of Neuropeptide Y and Other Related Factors in Breast Cancer and Osteoporosis
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TLDR
In this article, the relationship between breast cancer and osteoporosis, the influence of NPY on both diseases, and the recent progress in the research and treatment of these diseases are reviewed.Citations
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Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling.
Hyunook Kang,Chaehee Park,Yeol Kyo Choi,Jungnam Bae,Sohee Kwon,Jinuk Kim,C. Choi,Chaok Seok,Wonpil Im,Hee-Jung Choi +9 more
TL;DR: In this paper , the authors reported the structures of the PYY(3-36) and Y2R/Y2Gi complexes and revealed the molecular basis of the exclusive binding of peptide YY(3 -36) to y2R.
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Sex-specific bi‑directional association between osteoporosis and depression from the national representative data of South Korea
TL;DR: In this paper , the associations between osteoporosis and depression while considering the temporal sequence of the diagnoses were elucidated, and a reverse association was also assessed, where male depression patients aged under 50 years showed higher odds ratio (OR 9.16, 95% CI 1.78-47.18).
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ERBB2 as a prognostic biomarker correlates with immune infiltrates in papillary thyroid cancer
TL;DR: In this article , the authors explored the relationship between ERBB2 expression and prognosis, tumor phenotypes of interest, and immune infiltrates in PTC, and concluded that ERBB 2 may serve as a prognostic biomarker and an immunotherapeutic target in Papillary thyroid cancer.
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Dynamic <i>in Situ</i> Confinement Triggers Ligand-Free Neuropeptide Receptor Signaling
TL;DR: In this article , a chelator nanotool was used to induce the formation of neuropeptide Y2 hormone receptors (Y2R) in situ by a dynamic exchange of histidine-tagged Y2R within clusters.
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Neuropeptide Y Peptide Family and Cancer: Antitumor Therapeutic Strategies
TL;DR: In this article , the authors reviewed the involvement of neuropeptide Y (NPY), peptide YY (PYY), and pancreatic polypeptides (PP) and their receptors (YRs) in cancer.
References
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Journal ArticleDOI
Osteoclast differentiation and activation
TL;DR: Discovery of the RANK signalling pathway in the osteoclast has provided insight into the mechanisms of osteoporosis and activation of bone resorption, and how hormonal signals impact bone structure and mass.
Journal ArticleDOI
Risk Factors and Preventions of Breast Cancer.
Yi Sheng Sun,Zhao Zhao,Zhang Nv Yang,Fang Xu,Hang Jing Lu,Zhi Yong Zhu,Wen Shi,Jianmin Jiang,Ping Ping Yao,Han Ping Zhu +9 more
TL;DR: This review will summarize key studies of pathogenesis, related genes, risk factors and preventative methods on breast cancer over the past years and represent a small step in the long fight against breast cancer.
Journal ArticleDOI
Breastfeeding and maternal health outcomes: a systematic review and meta-analysis
Ranadip Chowdhury,Bireshwar Sinha,Mari Jeeva Sankar,Sunita Taneja,Nita Bhandari,Nigel Rollins,Rajiv Bahl,Jose Martines +7 more
TL;DR: A systematic literature search was conducted in PubMed Cochrane Library and CABI databases to evaluate the effect of breastfeeding on longterm (breast carcinoma ovarian carcinoma osteoporosis and type 2 diabetes mellitus) and short-term (lactational amenorrhoea post-partum depression postpartum weight change) maternal health outcomes.
Journal ArticleDOI
Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials
Joop P. W. van den Bergh,Kathleen I. Pritchard,KS Albain,Stewart J. Anderson,Rodrigo Arriagada,William E. Barlow,W. Bergsten-Nordström,Judith M Bliss,Francesco Boccardo,Rosie Bradley,Marc Buyse,David Cameron,Mike Clarke,M. Coates,Robert E. Coleman,C Correa,J. Costantino,Jack Cuzick,Neville Davidson,C Davies,A. Di Leo,Mitchell Dowsett,Marianne Ewertz,John F. Forbes,R. D. Gelber,R. Geyer,R. Gianni,M. Gnant,A. Goldhirsch,Richard Gray,Daniel F. Hayes,C. Hill,JN Ingle,Wolfgang Janni,Elizabeth MacKinnon,M. Martin,Paul McGale,Larry Norton,Yasuo Ohashi,Soonmyung Paik,Hongchao Pan,E. A. Perez,Richard Peto,R. Piccart,Lori J. Pierce,Vinod Raina,Peter M. Ravdin,J.F.R. Robertson,E.J.T. Rutgers,Joseph A. Sparano,Sandra M. Swain,Carolyn W. Taylor,Giuseppe Viale,G. von Minckwitz,Xiang Wang,Timothy J. Whelan,Nicholas Wilcken,Eric P. Winer,Norman Wolmark,William C. Wood +59 more
TL;DR: In this paper, the authors conducted a collaborative meta-analysis to clarify the risks and benefits of adjuvant bisphosphonate treatment in early breast cancer, and found that the reduction in bone recurrence was more definite (0.73-0.94; 2p=0.004).
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Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells
Makiko Ono,Nobuyoshi Kosaka,Naoomi Tominaga,Yusuke Yoshioka,Fumitaka Takeshita,Ryou U. Takahashi,Masayuki Yoshida,Hitoshi Tsuda,Kenji Tamura,Takahiro Ochiya +9 more
TL;DR: Findings suggest that exosomal transfer of miRNAs from the bone marrow may promote breast cancer cell dormancy in a metastatic niche.