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Journal ArticleDOI

Vacuna nonavalente frente al virus del papiloma humano. Actualización 2017

TLDR
The purpose of this publication is to provide healthcare professionals with the scientific evidence that supports the new vaccine, as well as the clinical value that it offers in the authors' environment.
Abstract
Human papillomavirus (HPV) is the causative agent of 5% of human cancers HPV infection is necessary for the development of cervical cancer and is responsible of a variable percentage of cancers of anus, vulva, vagina, penis, and oropharynx Since 2007, 2 vaccines against HPV have been commercially available in Spain: bivalent (HPV types 16/18), and tetravalent (HPV types 6/11/16/18) In order to extend the protection afforded by HPV vaccines, a clinical program was launched in 2006 for the new nonavalent vaccine, including 9 HPV types (6/11/16/18/31/33/45/52/58) These types are responsible for 90% of cervical cancers, 82% of high-grade ano-genital pre-cancerous lesions, and 90% of genital warts The purpose of this publication is to provide healthcare professionals with the scientific evidence that supports the new vaccine, as well as the clinical value that it offers in our environment

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Citations
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Epidemiologic and economic burden of HPV diseases in Spain: implication of additional 5 types from the 9-valent vaccine.

TL;DR: The aim of the present study was to estimate the annual direct costs associated to the following HPV-related diseases: genital warts, high grade precancerous lesions and cancer of cervix, vulva, vagina, anus and penis and head and neck cancer, caused by genotypes included in the nonavalent and quadrivalent vaccines, in Spanish men and women.
Journal ArticleDOI

Calendario de vacunaciones de la Asociación Española de Pediatría (CAV-AEP): recomendaciones 2018

TL;DR: Se aconseja un refuerzo a los 6 anos, preferentemente con DTPa, junto a una dosis de polio para aquellos que recibieron esquemas 2+1, asi como vacunacion con Tdpa en adolescentes y in cada embarazo, entre la 27 y 32 semanas.
Journal ArticleDOI

[Immunisation schedule of the Spanish Association of Paediatrics: 2018 recommendations].

TL;DR: Tetravalent meningococcal vaccine (MenACWY) is recommended to adolescents (14-18 years) who are going to live in countries with systematic vaccination against ACWY serogroups, and people >6 weeks of age with risk factors or travellers to countries with very high incidence.
References
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Journal ArticleDOI

The biology and life-cycle of human papillomaviruses.

TL;DR: The high-risk HPV types are a cause of several important human cancers, including almost all cases of cervical cancer, a large proportion of other anogenital cancers and a growing number of head and neck tumours.
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Use of a 2-Dose Schedule for Human Papillomavirus Vaccination - Updated Recommendations of the Advisory Committee on Immunization Practices.

TL;DR: Recommendations and guidance regarding use of HPV vaccines are provided and new recommendations for use of a 2-dose schedule for girls and boys who initiate the vaccination series at ages 9 through 14 years are included.
Journal ArticleDOI

Is vaccination with quadrivalent HPV vaccine after loop electrosurgical excision procedure effective in preventing recurrence in patients with high-grade cervical intraepithelial neoplasia (CIN2–3)?

TL;DR: Vaccination with the quadrivalent HPV vaccine after treatment may be considered in preventing recurrence of CIN2-3.