Validating posttransplant hepatocellular carcinoma recurrence data in the united network for organ sharing database
Reads0
Chats0
TLDR
The observed HCC recurrence rate was not significantly lower than the expected rate at any center, and this suggests that no systematic underreporting has occurred, and the OPTN H CC recurrence data supports their potential for further analysis.About:
This article is published in Liver Transplantation.The article was published on 2013-12-01 and is currently open access. It has received 24 citations till now. The article focuses on the topics: Transplantation & Liver transplantation.read more
Citations
More filters
Journal ArticleDOI
Time to transplantation as a predictor of hepatocellular carcinoma recurrence after liver transplantation
TL;DR: The risk of HCC recurrence within the first year after transplantation may be lessened by the institution of a mandatory waiting time after an exception is granted, as compared with rapid transplant patients and their slower transplant counterparts.
Journal ArticleDOI
Alpha-Fetoprotein Decrease from > 1,000 to < 500 ng/mL in Patients with Hepatocellular Carcinoma Leads to Improved Posttransplant Outcomes.
TL;DR: Evaluating the effects of a reduction in AFP from > 1,000 ng/mL to different AFP thresholds before LT on survival and HCC recurrence after LT demonstrated significantly improved post-LT outcomes, validating the recently implemented national policy.
Journal ArticleDOI
Validation of the prognostic power of the RETREAT score for hepatocellular carcinoma recurrence using the UNOS database.
TL;DR: This study validates the prognostic power of RETREAT, which may help standardize post‐LT surveillance, provide a framework for tumor staging and risk stratification, and select candidates for adjuvant therapies.
Journal ArticleDOI
Donor characteristics and risk of hepatocellular carcinoma recurrence after liver transplantation
Lorenzo A. Orci,Thierry Berney,Pietro Majno,Stéphanie Lacotte,Graziano Oldani,Philippe Morel,Gilles Mentha,Christian Toso +7 more
TL;DR: The impact of donor characteristics and graft quality on post‐transplant HCC recurrence and the risk of recurrence has been investigated.
Journal ArticleDOI
Alpha-Fetoprotein Slope >7.5 ng/mL per Month Predicts Microvascular Invasion and Tumor Recurrence After Liver Transplantation for Hepatocellular Carcinoma
TL;DR: AFP slope increasing greater than 7.5 ng/mL per month despite locoregional therapy is associated with post-LT HCC recurrence and may serve as a surrogate for microvascular invasion.
References
More filters
Journal ArticleDOI
Characteristics associated with liver graft failure: the concept of a donor risk index.
Sandy Feng,Nathan P. Goodrich,Jennifer L. Bragg-Gresham,Dawn M. Dykstra,J. D. Punch,M. A. DebRoy,S. M. Greenstein,Robert M. Merion +7 more
TL;DR: A quantitative donor risk index was developed using national data from 1998 to 2002 to assess the risk of donor liver graft failure using seven donor characteristics that independently predicted significantly increased risk of graft failure.
Journal ArticleDOI
Liver and intestine transplantation in the United States, 1997-2006.
Richard B. Freeman,D Steffick,Mary K. Guidinger,Douglas G. Farmer,Carl L. Berg,Robert M. Merion +5 more
TL;DR: Liver transplantation in 2006 generally resembled previous years, with fewer candidates waiting for deceased donor liver transplants (DDLT), continuing a trend initiated with the implementation of the model for end‐stage liver disease (MELD).
Journal ArticleDOI
New OPTN/UNOS Policy for Liver Transplant Allocation: Standardization of Liver Imaging, Diagnosis, Classification, and Reporting of Hepatocellular Carcinoma
Christoph Wald,Mark W. Russo,Julie K. Heimbach,Hero K. Hussain,Elizabeth A. Pomfret,Jordi Bruix +5 more
TL;DR: A new liver allocation policy featuring improved imaging criteria for hepatocellular carcinoma exceptions has been developed and approved by the Organ Procurement and Transplantation Network–United Network for Organ Sharing, in late 2011; radiologists in accredited transplantation centers in the United States are now challenged to implement the policy.
Journal ArticleDOI
Reassessing selection criteria prior to liver transplantation for hepatocellular carcinoma utilizing the Scientific Registry of Transplant Recipients database.
TL;DR: An overview of recipients of an isolated first liver transplant registered in the Scientific Registry of Transplant Recipients (SRTR) database shows that Milan criteria are too restrictive, and patients with larger TTV can enjoy satisfactory posttransplant survivals.
Journal ArticleDOI
Liver transplantation for hepatocellular carcinoma: impact of the MELD allocation system and predictors of survival.
TL;DR: The adoption of the MELD allocation system has led to a 6-fold increase in the proportion of transplantation patients with HCC, and patients with larger (3-5 cm) tumors, serum alpha-fetoprotein level >/=455 ng/mL, or a MELD score>/=20 have poor posttransplantation survival.
Related Papers (5)
Liver Transplantation for Hepatocellular Carcinoma: A Model Including α-Fetoprotein Improves the Performance of Milan Criteria
Christophe Duvoux,Françoise Roudot-Thoraval,Thomas Decaens,Fabienne Pessione,Hanaa Badran,Tullio Piardi,Claire Francoz,Philippe Compagnon,Claire Vanlemmens,Jérôme Dumortier,Sébastien Dharancy,Jean Gugenheim,Pierre-Henri Bernard,René Adam,Sylvie Radenne,Fabrice Muscari,Filomena Conti,Jean Hardwigsen,Georges-Philippe Pageaux,Olivier Chazouillères,Ephrem Salamé,M.N. Hilleret,Pascal Lebray,Armand Abergel,Marilyne Debette-Gratien,Michael D. Kluger,Ariane Mallat,Daniel Azoulay,Daniel Cherqui +28 more