Journal ArticleDOI
Virulence factors of Enterococcus faecalis and Enterococcus faecium blood culture isolates.
TLDR
The study showed that hemagglutinin and lipase may represent additional virulence factors of Enterococcus faecalis but not Enterococus faecium, and the significance of these factors in the pathogenesis of enterococcal infection needs to be elucidated in further studies.Abstract:
Known and potential virulence factors of enterococcal blood culture isolates were studied using 89 Enterococcus faecalis and 24 Enterococcus faecium isolates. The prevalence of the respective factors was (Enterococcus faecalis vs. Enterococcus faecium): hemolysin 16% vs. 0%, gelatinase 55% vs. 0%, aggregation substance 63% vs. 13%, lipase 35% vs. 4%, hemagglutinin 97% vs. 0%. Deoxyribonuclease was not detected in any isolate. The study showed that hemagglutinin and lipase may represent additional virulence factors of Enterococcus faecalis but not Enterococcus faecium. The significance of these factors in the pathogenesis of enterococcal infection needs to be elucidated in further studies.read more
Citations
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Journal ArticleDOI
Clinical relevance of the ESKAPE pathogens.
TL;DR: This review aims to consolidate clinically relevant background information on the ESKAPE pathogens and provide a contemporary summary of bacterial resistance, alongside pertinent microbiological considerations necessary to face the mounting threat of antimicrobial resistance.
Journal ArticleDOI
Mechanisms of Antimicrobial Resistance in ESKAPE Pathogens
TL;DR: This review summarized the known antimicrobial resistance mechanisms of ESKAPE pathogens to aid in the prediction of underlying or even unknown mechanisms of resistance, which could be applied to other emerging multidrug resistant pathogens.
Journal ArticleDOI
Enterococci in foods--a conundrum for food safety.
TL;DR: It is suggested that when considering an Enterococcus strain for use as a starter or probiotic culture, it is imperative that each particular strain should be carefully evaluated for the presence of all known virulence factors.
Journal ArticleDOI
Development of a Multiplex PCR for the Detection of asa1, gelE, cylA, esp, and hyl Genes in Enterococci and Survey for Virulence Determinants among European Hospital Isolates of Enterococcus faecium
Vanessa Vankerckhoven,Tim Van Autgaerden,Carl Vael,Christine Lammens,Sabine Chapelle,Rosaria Rossi,Daniela Jabes,Herman Goossens,Herman Goossens +8 more
TL;DR: The multiplex PCR reported in this study is a convenient and rapid method for the simultaneous detection of the virulence genes asa1, gelE, cylA, esp, and hyl in enterococci.
Journal ArticleDOI
Virulence factors of Enterococcus faecalis: relationship to endodontic disease.
Guven Kayaoglu,Dag Ørstavik +1 more
TL;DR: The most-cited virulence factors of E. faecalis are aggregation substance, surface adhesins, sex pheromones, lipoteichoic acid, extracellular superoxide production, the lytic enzymes gelatinase and hyaluronidase, and the toxin cytolysin.
References
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Journal ArticleDOI
The Clinical Significance of Positive Blood Cultures in the 1990s: A Prospective Comprehensive Evaluation of the Microbiology, Epidemiology, and Outcome of Bacteremia and Fungemia in Adults
Melvin P. Weinstein,M L Towns,S M Quartey,Stanley Mirrett,Larry G. Reimer,Giovanni Parmigiani,L B Reller +6 more
TL;DR: Bloodstream infections in the 1990s are notable for the increased importance of CNS as both contaminants and pathogens, the proportionate increase in fungi and decrease in anaerobes as pathogens,The emergence of Mycobacterium avium complex as an important cause of bacteremia in patients with advanced human immunodeficiency virus infection, and the reduction in mortality associated with infection.
Journal ArticleDOI
Identification of Enterococcus species isolated from human infections by a conventional test scheme.
Richard R. Facklam,M D Collins +1 more
TL;DR: Streptococci (206 cultures) previously identified as enterococci were retrieved from storage and reidentified by using tests designed to identify species of the genus Enterococcus by using DNA-DNA hybridizations to assure correct identification.
Journal ArticleDOI
Virulence of enterococci.
TL;DR: The current understanding of enterococcal virulence relating to adherence to host tissues, invasion and abscess formation, factors potentially relevant to modulation of host inflammatory responses, and potentially toxic secreted products are discussed.
Journal ArticleDOI
Induced cell aggregation and mating in Streptococcus faecalis: evidence for a bacterial sex pheromone
TL;DR: The data suggest that CIA represents a bacterial sex hormone (pheromone) which causes strains carrying certain conjugative plasmids to aggregate and induce donors to mate at high frequencies.
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