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Vitamin D and Prolonged Treatment with Photosensitivity-Associated Antibiotics

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TLDR
Vitamin D has important roles in physiological processes and is primarily involved in calcium and phosphorus homeostasis and musculoskeletal system metabolism.
Abstract
Vitamin D has important roles in physiological processes and is primarily involved in calcium and phosphorus homeostasis and musculoskeletal system metabolism ([1][1], [2][2]). Moreover, vitamin D acts on the cardiovascular system and in systemic inflammation, oxidative stress, and immune regulation

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Hydroxychloroquine Blood Levels in Systemic Lupus Erythematosus: Clarifying Dosing Controversies and Improving Adherence

TL;DR: It is shown that weight-based dosing (max 400 mg daily) is appropriate and that height does not appear to influence levels, and there was a trend toward higher disease activity with lower HCQ levels.
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Abnormal weight gain and gut microbiota modifications are side effects of long-term doxycycline and hydroxychloroquine treatment

TL;DR: The need for specific nutritional care in patients undergoing long-term antibiotic treatment, particularly treatment involving the use of doxycycline, is highlighted, as abnormal weight gain is a side effect of long- term doxy cycline and hydroxychloroquine treatment.
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Emergence of Q Fever Arthritis in France

TL;DR: Q fever articular infections could be undiagnosed because of the long evolution of articular attack, and patients with high antibody titers against C. burnetii should be tested using PET scanning to localize the site of infection.
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Doxycycline assay hair samples for testing long-term compliance treatment

TL;DR: Hair samples can be used to test long-term compliance in patients to explain failures or relapses and to use hair samples for monitoring the compliance over a longer period of time.
References
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Journal ArticleDOI

From vitamin D to hormone D: fundamentals of the vitamin D endocrine system essential for good health

TL;DR: The nutritional guidelines for vitamin D(3) intake should be reevaluated, taking into account the contributions to good health that all 36 VDR target organs can provide.
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Vitamin D supplementation enhances the beneficial effects of weight loss on cardiovascular disease risk markers

TL;DR: The results indicate that a vitamin D supplement of 83 microg/d does not adversely affect weight loss and is able to significantly improve several cardiovascular disease risk markers in overweight subjects with inadequate vitamin D status participating in a weight-reduction program.
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Levels of vitamin D and cardiometabolic disorders: Systematic review and meta-analysis

TL;DR: High levels of vitamin D among middle-age and elderly populations are associated with a substantial decrease in cardiovascular disease, type 2 diabetes and metabolic syndrome, and interventions targeting vitamin D deficiency in adult populations could potentially slow the current epidemics of cardiometabolic disorders.
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The link between obesity and low circulating 25-hydroxyvitamin D concentrations: considerations and implications.

TL;DR: Additional research is needed to elucidate the complex and multifaceted factors underlying the association between low circulating 25-hydroxyvitamin D and obesity, and to identify optimal treatment approaches in obese individuals and in bariatric surgical patients both before and after surgery.
Journal ArticleDOI

Safety of doxycycline and minocycline: a systematic review.

TL;DR: Although more head-to-head clinical trials are needed for a direct comparison of AE frequency, these preliminary data from separate reports suggest the possibility that AEs may be less likely with doxycycline than minocycline.
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