Journal ArticleDOI
Voriconazole versus a regimen of amphotericin B followed by fluconazole for candidaemia in non-neutropenic patients: a randomised non-inferiority trial
B J Kullberg,Jack D. Sobel,Markus Ruhnke,Peter G. Pappas,Claudio Viscoli,John H. Rex,John D. Cleary,E Rubinstein,L W P Church,J M Brown,Haran T. Schlamm,I T Oborska,F Hilton,Michael R. Hodges +13 more
TLDR
Voriconazole was as effective as the regimen of amphotericin B followed by fluconazole in the treatment of candidaemia in non-neutropenic patients, and with fewer toxic effects.About:
This article is published in The Lancet.The article was published on 2005-10-22. It has received 492 citations till now. The article focuses on the topics: Voriconazole & Amphotericin B.read more
Citations
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Journal ArticleDOI
Epidemiology of Invasive Candidiasis: a Persistent Public Health Problem
TL;DR: Improved non-culture-based diagnostics are needed to expand the potential for preemptive (or early directed) therapy and improve diagnostic, preventive, and therapeutic strategies is necessary to reduce the considerable morbidity and mortality associated with IC.
Journal ArticleDOI
Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America.
Peter G. Pappas,Carol A. Kauffman,David R. Andes,Daniel K. Benjamin,Thierry Calandra,John E. Edwards,Scott G. Filler,John F. Fisher,Bart Jan Kullberg,Luis Ostrosky-Zeichner,Annette C. Reboli,John H. Rex,Thomas J. Walsh,Jack D. Sobel +13 more
TL;DR: These updated guidelines replace the previous guidelines published in the 15 January 2004 issue of Clinical Infectious Diseases and are intended for use by health care providers who care for patients who either have or are at risk of these infections.
Journal ArticleDOI
Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America
Alison G. Freifeld,Eric J. Bow,Kent A. Sepkowitz,Michael Boeckh,James I. Ito,Craig A. Mullen,Issam I Raad,Kenneth V. I. Rolston,Jo Anne H. Young,John R. Wingard,Fred Hutchinson +10 more
TL;DR: This document updates and expands the initial Infectious Diseases Society of America (IDSA) Fever and Neutropenia Guideline that was published in 1997 and first updated in 2002 and developed a clearer definition of which populations of patients with cancer may benefit most from antibiotic, antifungal, and antiviral prophylaxis.
Journal ArticleDOI
Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America
Peter G. Pappas,Carol A. Kauffman,David R. Andes,Cornelius J. Clancy,Kieren A. Marr,Luis Ostrosky-Zeichner,Annette C. Reboli,Mindy G. Schuster,Jose A. Vazquez,Thomas J. Walsh,Theoklis E. Zaoutis,Jack D. Sobel +11 more
TL;DR: IDSA considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient's individual circumstances.
Journal ArticleDOI
Burn Wound Infections
TL;DR: Improved outcomes for severely burned patients have been attributed to medical advances in fluid resuscitation, nutritional support, pulmonary and burn wound care, and infection control practices.
References
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Journal ArticleDOI
Voriconazole versus Amphotericin B for Primary Therapy of Invasive Aspergillosis
Raoul Herbrecht,David W. Denning,David W. Denning,Thomas F. Patterson,John E. Bennett,Reginald Greene,Reginald Greene,J. W. Oestmann,Winfried V. Kern,Winfried V. Kern,Winfried V. Kern,Kieren A. Marr,Patricia Ribaud,Olivier Lortholary,Richard J. Sylvester,Robert H. Rubin,John R. Wingard,Paul Stark,Christine Durand,Denis Caillot,Eckhard Thiel,Pranatharthi H. Chandrasekar,Michael R. Hodges,Haran T. Schlamm,Peter F. Troke,Ben E. De Pauw +25 more
TL;DR: In patients with invasive aspergillosis,Initial therapy with voriconazole led to better responses and improved survival and resulted in fewer severe side effects than the standard approach of initial therapy with amphotericin B.
Journal ArticleDOI
Guidelines for Treatment of Candidiasis
Peter G. Pappas,John H. Rex,Jack D. Sobel,Scott G. Filler,William E. Dismukes,Thomas J. Walsh,John E. Edwards +6 more
TL;DR: This work presents a novel and scalable approach that allows for real-time decision-making about whether or not to vaccinate children against infection by a single infectious agent.
Journal ArticleDOI
Comparison of caspofungin and amphotericin B for invasive candidiasis.
Jorge Mora-Duarte,Robert F. Betts,Coleman Rotstein,Arnaldo Lopes Colombo,Luis Thompson-Moya,Juanita M Smietana,Robert J. Lupinacci,Carole A. Sable,Nicholas A. Kartsonis,John R. Perfect +9 more
TL;DR: Caspofungin is at least as effective as amphotericin B for the treatment of invasive candidiasis and, more specifically, candidemia.
Journal ArticleDOI
A Randomized Trial Comparing Fluconazole with Amphotericin B for the Treatment of Candidemia in Patients without Neutropenia
John H. Rex,John E. Bennett,Alan M. Sugar,Peter G. Pappas,Charles van der Horst,John E. Edwards,Ronald G. Washburn,W. Michael Scheld,Adolf W. Karchmer,Alan P. Dine,Marcia Levenstein,C. Douglas Webb +11 more
TL;DR: A multicenter randomized trial that compared amphotericin B with fluconazole as treatment for candidemia, with the most common diagnoses being renal failure, nonhematologic cancer, and gastrointestinal disease.
Journal ArticleDOI
Efficacy and Safety of Voriconazole in the Treatment of Acute Invasive Aspergillosis
David W. Denning,Patricia Ribaud,Noel Milpied,Denis Caillot,Raoul Herbrecht,Eckhard Thiel,Andrea Haas,Markus Ruhnke,Hartmut Lode +8 more
TL;DR: Voriconazole is efficacious in treating acute IA and is proven and probable in 68 patients, and good responses were seen in 60% of those with pulmonary or tracheobronchial IA and 26% of allogeneic stem cell transplant recipients.
Related Papers (5)
Voriconazole versus Amphotericin B for Primary Therapy of Invasive Aspergillosis
Raoul Herbrecht,David W. Denning,David W. Denning,Thomas F. Patterson,John E. Bennett,Reginald Greene,Reginald Greene,J. W. Oestmann,Winfried V. Kern,Winfried V. Kern,Winfried V. Kern,Kieren A. Marr,Patricia Ribaud,Olivier Lortholary,Richard J. Sylvester,Robert H. Rubin,John R. Wingard,Paul Stark,Christine Durand,Denis Caillot,Eckhard Thiel,Pranatharthi H. Chandrasekar,Michael R. Hodges,Haran T. Schlamm,Peter F. Troke,Ben E. De Pauw +25 more