What should the optimal target hemoglobin be?1
TLDR
While the majority of patients with CKD may experience significant benefits when Hb is normalized, it seems prudent to recommend individualized target Hb concentrations for each patient, taking into account factors such as age, sex, employment status, physical activity, and co-morbidities.About:
This article is published in Kidney International.The article was published on 2002-05-01 and is currently open access. It has received 19 citations till now. The article focuses on the topics: Kidney disease & Anemia.read more
Citations
More filters
Journal ArticleDOI
A prospective study of anemia status, hemoglobin concentration, and mortality in an elderly cohort: the Cardiovascular Health Study.
Neil A. Zakai,Ronit Katz,Calvin H. Hirsch,Michael G. Shlipak,Paulo H.M. Chaves,Anne B. Newman,Mary Cushman +6 more
TL;DR: In this article, the authors assessed baseline hemoglobin quintiles and anemia in relation to mortality in the Cardiovascular Health Study, a prospective cohort study with 11.2 years of follow-up of 5888 community-dwelling men and women 65 years or older, enrolled in 1989-1990 or 1992-1993 in 4 US communities.
Journal ArticleDOI
The story so far: molecular regulation of the heme oxygenase-1 gene in renal injury
TL;DR: This review will focus on the molecular regulation of the HO-1 gene in renal injury and will highlight the interspecies differences, predominantly between the rodent and humanHO-1 genes.
Journal ArticleDOI
Anemia and mortality in hemodialysis patients: accounting for morbidity and treatment variables updated over time.
Bruce M. Robinson,Marshall M. Joffe,Jeffrey S. Berns,Ronald L. Pisoni,F. K. Port,Harold I. Feldman +5 more
TL;DR: The findings confirm the associations of Hb levels > or =11 g/dL with longer survival among maintenance hemodialysis patients, but show no additional survival advantage for patients with HB levels >or =12 g/DL.
Journal ArticleDOI
Optimal anemia management reduces cardiovascular morbidity, mortality, and costs in chronic kidney disease
TL;DR: The fundamental impact of anemia on organ function is reduced oxygen delivery to tissues, but other consequences such as impaired cognitive function and concentration, sleep disorders, altered hemostasis, depressed immune function, and impaired cardiac function are not uncommon.
Journal ArticleDOI
Prevalence, Types, Risk Factors and Clinical Correlates of Anaemia in Older People in a Rural Ugandan Population
TL;DR: Anaemia control programmes in Uganda should target older people and should include interventions to treat and control hookworms and educational programs on diets that enhance iron absorption.
References
More filters
Journal ArticleDOI
The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin.
Anatole Besarab,W K Bolton,J K Browne,Joan C. Egrie,Allen R. Nissenson,D M Okamoto,Steve J. Schwab,David A. Goodkin +7 more
TL;DR: In patients with clinically evident congestive heart failure or ischemic heart disease who are receiving hemodialysis, administration of epoetin to raise their hematocrit to 42 percent is not recommended.
Journal ArticleDOI
Left ventricular mass index increase in early renal disease: impact of decline in hemoglobin.
Adeera Levin,Christopher R. Thompson,Jean Ethier,Euan Carlisle,Sheldon W. Tobe,David C. Mendelssohn,Ellen Burgess,Kailash Jindal,Brendan J. Barrett,Joel Singer,Ognjenka Djurdjev +10 more
TL;DR: There remains a critical need to establish optimal therapeutic strategies and targets to improve clinical outcomes in patients with progressive renal disease, and the important modifiable risk factors are defined.
Journal ArticleDOI
The impact of anemia on cardiomyopathy, morbidity, and mortality in end-stage renal disease☆
Robert N. Foley,Patrick S. Parfrey,Patrick S. Parfrey,John D. Harnett,John D. Harnett,Gloria M. Kent,Gloria M. Kent,David C. Murray,David C. Murray,Paul E. Barre,Paul E. Barre +10 more
TL;DR: Anemia, an easily reversible feature of end- stage renal disease, is an independent risk factor for clinical and echocardiographic cardiac disease, as well as mortality in end-stage renal disease patients.
Journal ArticleDOI
Prevalent left ventricular hypertrophy in the predialysis population: Identifying opportunities for intervention☆☆☆
TL;DR: The high prevalence ofLVH in patients with renal insufficiency prior to the need for dialysis is demonstrated, which is associated with severity of renal impairment, and two modifiable factors (systolic blood pressure and anemia) are identified as important predictors of LVH.
Journal ArticleDOI
Hematocrit Level and Associated Mortality in Hemodialysis Patients
TL;DR: Overall, the findings suggest that sustained increases in hematocrit levels are associated with improved patient survival, and patients with hematOCrit levels of 33% to less than 36% appear to have the lowest risk for all-cause and cardiac mortality.