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Working toward rational and evidence-based treatment of chronic subdural hematoma.

TLDR
This review focuses on the pathophysiology of chronic subdural hematoma and briefly discusses the epidemiology, clinical presentation, and surgical treatments of CSDH, concluding that a one-for-all management strategy is not appropriate.
Abstract
Chronic subdural hematoma (CSDH) is one of the most common neurosurgical conditions that can usually be treated with relatively simple and effective surgical procedures. It affects primarily the elderly, a rising population worldwide. Together with improved awareness among the medical profession and greater access to modern imaging facilities, the incidence of CSDH is set to rise significantly. Maximization of the efficiency of management of CSDH is therefore a priority. To this end, a review of the findings of clinical and laboratory research underpinning the basis of the modern management of CSDH has been carried out. This review focuses on the pathophysiology and briefly discusses the epidemiology, clinical presentation, and surgical treatments of CSDH, concluding that a one-for-all management strategy is not appropriate. Creating rational bases for the selection of an ideal treatment strategy for an individual patient should be the target. This can be achieved through better understanding of the nature of the condition through systematic basic science research, ascertaining the merits of different surgical techniques in well-designed and rigorously executed clinical trials, using advances in imaging techniques to classify CSDH (a subject not addressed here), and training in and ongoing refinement of clinical acumen and surgical skills of individual surgeons.

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Citations
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Journal ArticleDOI

Chronic subdural hematoma management: a systematic review and meta-analysis of 34,829 patients.

TL;DR: Percutaneous bedside twist-drill drainage is a relatively safe and effective first-line management option for chronic subdural hematoma patients with CSDH and may result in potential health cost savings and eliminate perioperative risks related to general anesthetic.
Journal ArticleDOI

Chronic subdural haematoma: modern management and emerging therapies

TL;DR: An overview of the contemporary management of chronic subdural haematoma is provided and considerations regarding future approaches that could further optimize patient care and outcomes are presented.
Journal ArticleDOI

Chronic Subdural Hematoma: Epidemiology and Natural History.

TL;DR: The epidemiology and natural history of chronic subdural hematoma, a common disease prevalent in the elderly population, and nonsurgical predictive factors are described in detail to provide a comprehensive understanding of the outcome of this disease.
Journal ArticleDOI

Chronic subdural hematoma.

TL;DR: Better understanding of the nature of the pathology, rational selection of an ideal treatment strategy for an individual patient, and identification of the merits and limitations of different surgical techniques could help in improving the prognosis of chronic subdural hematoma.
Journal ArticleDOI

Middle Meningeal Artery Embolization for Chronic Subdural Hematoma: Meta-Analysis and Systematic Review

TL;DR: In this article, a meta-analysis and systematic review of the use of middle meningeal artery (MMA) embolization for chronic subdural hematoma is presented.
References
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The role of vascular endothelial growth factor in wound healing.

TL;DR: Experimental data supports the hypothesis that VEGF stimulates epithelialization and collagen deposition in a wound, but likely promotes collagen deposition and epithelization as well, and stimulates wound healing through angiogenesis.
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Chronic subdural hematomas" a review

TL;DR: Present knowledge of the still controversial pathogenetic, ultrastructural, diagnostic, and treatment aspects of chronic subdural hematomas is reviewed.
Journal ArticleDOI

Surgical treatment of chronic subdural hematoma in 500 consecutive cases: clinical characteristics, surgical outcome, complications, and recurrence rate.

TL;DR: Old age, pre-existing cerebral infarction, and persistence of subdural air after surgery were significantly correlated with poor brain re-expansion (p < 0.001), which will further improve the surgical outcome for patients with CSDH.
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