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Adam J. Schwarz
Researcher at Eli Lilly and Company
Publications - 138
Citations - 7833
Adam J. Schwarz is an academic researcher from Eli Lilly and Company. The author has contributed to research in topics: Resting state fMRI & Medicine. The author has an hindex of 46, co-authored 124 publications receiving 6662 citations. Previous affiliations of Adam J. Schwarz include Indiana University & Takeda Pharmaceutical Company.
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Journal ArticleDOI
CNVs conferring risk of autism or schizophrenia affect cognition in controls
Hreinn Stefansson,Andreas Meyer-Lindenberg,Stacy Steinberg,Brynja B. Magnusdottir,Katrin Morgen,Sunna Arnarsdottir,Gyda Bjornsdottir,G. Bragi Walters,Gudrun A. Jonsdottir,Orla Doyle,Heike Tost,Oliver Grimm,Solveig Kristjansdottir,Heimir Snorrason,Solveig Davidsdottir,Larus J. Gudmundsson,Gudbjorn F. Jonsson,Berglind Stefansdottir,Isafold Helgadottir,Magnús Haraldsson,Birna Jonsdottir,Johan H. Thygesen,Adam J. Schwarz,Michael Didriksen,Tine B. Stensbøl,Michael Brammer,Shitij Kapur,Jonas G. Halldorsson,Stefan Hreidarsson,Evald Saemundsen,Engilbert Sigurdsson,Kari Stefansson +31 more
TL;DR: It is shown in an Icelandic sample that a few of the CNVs clearly alter fecundity (measured as the number of children by age 45), and various tests of cognitive function are used to demonstrate that control subjects carrying theCNVs perform at a level that is between that of schizophrenia patients and population controls.
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Regional profiles of the candidate tau PET ligand 18F-AV-1451 recapitulate key features of Braak histopathological stages.
Adam J. Schwarz,Peng Yu,Bradley B. Miller,Sergey Shcherbinin,James Dickson,Michael Navitsky,Abhinay D. Joshi,Michael D. Devous,Mark S. Mintun +8 more
TL;DR: The estimated Braak stage was significantly associated with amyloid status, diagnostic category and measures of global cognition and could be classified into patterns similar to those prescribed by Braak neuropathological staging of tau pathology.
Journal ArticleDOI
A stereotaxic MRI template set for the rat brain with tissue class distribution maps and co-registered anatomical atlas: application to pharmacological MRI.
Adam J. Schwarz,Anne Danckaert,Torsten Reese,Alessandro Gozzi,George Paxinos,Charles Watson,Emilio Merlo-Pich,Angelo Bifone +7 more
TL;DR: A stereotaxic rat brain MRI template set with a co-registered digital anatomical atlas is described and its application to the analysis of a pharmacological MRI study of apomorphine is illustrated.
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Test–retest reliability of evoked BOLD signals from a cognitive–emotive fMRI test battery
Michael M. Plichta,Adam J. Schwarz,Oliver Grimm,Katrin Morgen,Daniela Mier,Leila Haddad,Antje B. M. Gerdes,Carina Sauer,Heike Tost,Christine Esslinger,Christine Esslinger,P. Colman,Frederick Wilson,Peter Kirsch,Andreas Meyer-Lindenberg +14 more
TL;DR: All three tasks in the combined three-task fMRI battery targeting three systems of wide applicability in clinical and cognitive neuroscience are well suited to between-subject designs, including imaging genetics.
Journal ArticleDOI
Quantitative imaging biomarkers: a review of statistical methods for technical performance assessment.
David Raunig,Lisa M. McShane,Gene Pennello,Constantine Gatsonis,Paul L. Carson,James T. Voyvodic,Richard L. Wahl,Brenda F. Kurland,Adam J. Schwarz,Mithat Gonen,Gudrun Zahlmann,Marina Kondratovich,Kevin O'Donnell,Nicholas Petrick,Patricia E. Cole,Brian S. Garra,Daniel C. Sullivan +16 more
TL;DR: This document provides a consistent framework for the conduct and evaluation of quantitative imaging biomarker performance studies so that results from multiple studies can be compared, contrasted, or combined.