A
Agathe Jouet
Researcher at Norwich Research Park
Publications - 11
Citations - 275
Agathe Jouet is an academic researcher from Norwich Research Park. The author has contributed to research in topics: Oomycete & Phytophthora infestans. The author has an hindex of 7, co-authored 8 publications receiving 155 citations. Previous affiliations of Agathe Jouet include University of East Anglia.
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Journal ArticleDOI
A sister lineage of the Mycobacterium tuberculosis complex discovered in the African Great Lakes region
Jean Claude Semuto Ngabonziza,Chloé Loiseau,Chloé Loiseau,Michael Marceau,Agathe Jouet,Fabrizio Menardo,Fabrizio Menardo,Oren Tzfadia,Rudy Antoine,Esdras Belamo Niyigena,Wim Mulders,K Fissette,Maren Diels,Cyril Gaudin,Stéphanie Duthoy,Willy Ssengooba,Emmanuel André,Michel K. Kaswa,Yves Mucyo Habimana,Daniela Brites,Daniela Brites,Dissou Affolabi,Jean Baptiste Mazarati,Bouke C. de Jong,Leen Rigouts,Sebastien Gagneux,Sebastien Gagneux,Conor J. Meehan,Conor J. Meehan,Philip Supply +29 more
TL;DR: Two MTBC strains isolated from patients with multidrug resistant tuberculosis are identified, representing an as-yet-unknown lineage, named Lineage 8 (L8), seemingly restricted to the African Great Lakes region, further supporting an East African origin for the MTBC.
Journal ArticleDOI
Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs
Agathe Jouet,Cyril Gaudin,Nelly Badalato,Caroline Allix-Béguec,Stéphanie Duthoy,Alice Ferré,Maren Diels,Yannick Laurent,Sandy Contreras,Silke Feuerriegel,Stefan Niemann,Emmanuel André,Michel K. Kaswa,Elisa Tagliani,Andrea M. Cabibbe,Vanessa Mathys,Daniela Maria Cirillo,Bouke C. de Jong,Leen Rigouts,Philip Supply +19 more
TL;DR: The novel Deeplex Myc-TB targeted deep-sequencing assay shows a high degree of accuracy for extensive prediction of susceptibility and resistance to 13 anti-tuberculous drugs, directly achievable without culture, which may enable fast, tailored tuberculosis treatment.
Journal ArticleDOI
Albugo candida race diversity, ploidy and host-associated microbes revealed using DNA sequence capture on diseased plants in the field.
Agathe Jouet,Agathe Jouet,Diane G. O. Saunders,Mark McMullan,Ben J. Ward,Ben J. Ward,Oliver J. Furzer,Oliver J. Furzer,Florian Jupe,Florian Jupe,Volkan Cevik,Volkan Cevik,Ingo Hein,Gaetan Thilliez,Gaetan Thilliez,Eric B. Holub,Cock van Oosterhout,Jonathan D. G. Jones +17 more
TL;DR: It is shown that targeted sequencing has a great potential for the study of pathogen populations while they are colonizing their hosts, and this method could be applied to other microbes, especially to those that cannot be cultured.
Journal ArticleDOI
Pathogen enrichment sequencing (PenSeq) enables population genomic studies in oomycetes
Gaetan Thilliez,Miles R. Armstrong,Tze-Yin Lim,Katie Baker,Agathe Jouet,Ben J. Ward,Cock van Oosterhout,Jonathan D. G. Jones,Edgar Huitema,Paul R. J. Birch,Ingo Hein +10 more
TL;DR: PenSeq represents a cost‐effective alternative to whole‐genome sequencing and addresses crucial limitations of current plant pathogen population studies, which are often based on selectively neutral markers and consequently have limited utility in the analysis of adaptive evolution.
Journal ArticleDOI
Identification of Avramr1 from Phytophthora infestans using long read and cDNA pathogen-enrichment sequencing (PenSeq).
Xiao Lin,Tianqiao Song,Sebastian Fairhead,Kamil Witek,Agathe Jouet,Florian Jupe,Agnieszka I. Witek,Hari S. Karki,Vivianne G. A. A. Vleeshouwers,Ingo Hein,Ingo Hein,Jonathan D. G. Jones +11 more
TL;DR: Key insights are revealed into the evolution and polymorphism of a complex RXLR effector family that is associated with the recognition by Rpi‐amr1, and it is demonstrated that long read and cDNA PenSeq enables the identification of full‐length RX LR effector families and their expression profile.