Agnieszka Sekowska

TL;DR: To estimate the minimal gene set required to sustain bacterial life in nutritious conditions, a systematic inactivation of Bacillus subtilis genes was carried out and most genes involved in the Embden–Meyerhof–Parnas pathway are essential.

TL;DR: The situation in Escherichia coli and related bacteria, where more than one hundred genes involved in sulfur metabolism have already been discovered, is reviewed, and the involvement of methionine as the universal start of proteins as well as its derivative S-adenosylmethionine in a vast variety of cell processes argue in favour of a major importance of sulfur metabolism in all organisms.

TL;DR: Using variance analysis it is possible to distinguish between systematic biases and relevant gene-expression variation in transcriptome experiments and co-variation of metabolic gene expression pathways was uncovered linking nitrogen and sulfur metabolism in B. subtilis.

TL;DR: The gap tree gives a consistent picture of functional kinship, perhaps reflecting some aspects of phylogeny, with a clear domain of enzymes encoding two types of urehydrolases (agmatinases and arginases) and activities related to, but different from ureohydrolases.

TL;DR: Spermidine biosynthesis in Gram‐positive bacteria and in archaea follows a pathway very similar to that of Gram‐negatives and eukarya, indicating that polyamine metabolism to sulphur and carbon metabolism by a so far unknown mechanism is coupleed.