A
Aki S. Havulinna
Researcher at National Institute for Health and Welfare
Publications - 57
Citations - 2654
Aki S. Havulinna is an academic researcher from National Institute for Health and Welfare. The author has contributed to research in topics: Population & Prospective cohort study. The author has an hindex of 24, co-authored 57 publications receiving 2134 citations. Previous affiliations of Aki S. Havulinna include University of Helsinki & National Institutes of Health.
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Journal ArticleDOI
Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors
Ari Ahola-Olli,Peter Würtz,Aki S. Havulinna,Kristiina Aalto,Niina Pitkänen,Terho Lehtimäki,Mika Kähönen,Leo-Pekka Lyytikäinen,Emma Raitoharju,Ilkka Seppälä,Antti-Pekka Sarin,Samuli Ripatti,A. Palotie,Markus Perola,Jorma S. A. Viikari,Jorma S. A. Viikari,Sirpa Jalkanen,Mikael Maksimow,Veikko Salomaa,Marko Salmi,Johannes Kettunen,Olli T. Raitakari,Olli T. Raitakari,Olli T. Raitakari +23 more
TL;DR: In this paper, the causal roles of cytokine signaling and upstream inflammation in immune-related and other chronic diseases were clarified using a genome-wide association study (GWAS) of up to 8,293 Finns.
Journal ArticleDOI
Circulating Ceramides Predict Cardiovascular Outcomes in the Population-Based FINRISK 2002 Cohort.
Aki S. Havulinna,Marko Sysi-Aho,Mika Hilvo,Dimple Kauhanen,Reini Hurme,Kim Ekroos,Veikko Salomaa,Reijo Laaksonen +7 more
TL;DR: Distinct serum ceramides are associated with the risk of incident MACE in apparently healthy individuals and should encourage more detailed analyses of ceramide in cardiovascular pathobiology and suggest new biomarkers of MACE risk.
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Genome-Wide Screen for Metabolic Syndrome Susceptibility Loci Reveals Strong Lipid Gene Contribution but No Evidence for Common Genetic Basis for Clustering of Metabolic Syndrome Traits
Kati Kristiansson,Markus Perola,Emmi Tikkanen,Johannes Kettunen,Ida Surakka,Aki S. Havulinna,Alena Stančáková,Chris P. Barnes,Elisabeth Widen,Eero Kajantie,Johan G. Eriksson,Jorma S. A. Viikari,Mika Kähönen,Terho Lehtimäki,Olli T. Raitakari,Anna-Liisa Hartikainen,Aimo Ruokonen,Anneli Pouta,Antti Jula,Antti J. Kangas,Pasi Soininen,Mika Ala-Korpela,Satu Männistö,Pekka Jousilahti,Lori L. Bonnycastle,Marjo-Riitta Järvelin,Johanna Kuusisto,Francis S. Collins,Markku Laakso,Matthew E. Hurles,Aarno Palotie,Leena Peltonen,Samuli Ripatti,Veikko Salomaa +33 more
TL;DR: Genes from lipid metabolism pathways have the key role in the genetic background of MetS, and a genetic risk score, calculated as the number of risk alleles in loci associated with individual MetS traits, was strongly associated with MetS status.
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A metabolic view on menopause and ageing
Kirsi Auro,Anni Joensuu,Krista Fischer,Johannes Kettunen,Perttu Salo,Hannele Mattsson,Marjo Niironen,Jaakko Kaprio,Johan G. Eriksson,Terho Lehtimäki,Olli T. Raitakari,Antti Jula,Aila Tiitinen,Matti Jauhiainen,Pasi Soininen,Antti J. Kangas,Mika Kähönen,Aki S. Havulinna,Mika Ala-Korpela,Veikko Salomaa,Andres Metspalu,Markus Perola +21 more
TL;DR: It is suggested that, in addition to lipid alterations, menopause may contribute to future metabolic and cardiovascular risk via influencing amino-acid concentrations, adding to the growing evidence of the importance of amino acids in metabolic disease progression.
Journal ArticleDOI
Twenty-five-year trends in myocardial infarction attack and mortality rates, and case-fatality, in six European populations
Irene R. Dégano,Veikko Salomaa,Giovanni Veronesi,Jean Ferrières,Inge Kirchberger,Toivo Laks,Aki S. Havulinna,Jean-Bernard Ruidavets,Marco M Ferrario,Christa Meisinger,Roberto Elosua,Jaume Marrugat +11 more
TL;DR: In this paper, the authors examined the acute myocardial infarction (AMI) trends in attack and mortality rates, and in 28-day case-fatality, in six European populations during 1985-2010.