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Alexander Klimovich
Researcher at University of Kiel
Publications - 27
Citations - 610
Alexander Klimovich is an academic researcher from University of Kiel. The author has contributed to research in topics: Lernaean Hydra & Biology. The author has an hindex of 11, co-authored 24 publications receiving 421 citations. Previous affiliations of Alexander Klimovich include Saint Petersburg State University & Russian Academy of Sciences.
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Journal ArticleDOI
Naturally occurring tumours in the basal metazoan Hydra
Tomislav Domazet-Lošo,Alexander Klimovich,Borsi Anokhin,Friederike Anton-Erxleben,Maillin J. Hamm,Christina Lange,Thomas C. G. Bosch +6 more
TL;DR: First evidence for naturally occurring tumours in two species of Hydra is provided and shows that spontaneous tumours have deep evolutionary roots and that early branching animals may be informative in revealing the fundamental mechanisms of tumorigenesis.
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Back to the Basics: Cnidarians Start to Fire
Thomas C. G. Bosch,Alexander Klimovich,Tomislav Domazet-Lošo,Stefan Gründer,Thomas W. Holstein,Gáspár Jékely,David J. Miller,Andrea P. Murillo-Rincon,Fabian Rentzsch,Gemma S. Richards,Gemma S. Richards,Katja Schröder,Ulrich Technau,Rafael Yuste +13 more
TL;DR: Current knowledge on the nervous systems of cnidarian species are reviewed and it is proposed that researchers should seize this opportunity and undertake the study of members of this phylum as strategic experimental systems with great basic and translational relevance for neuroscience.
Journal ArticleDOI
Spontaneous body contractions are modulated by the microbiome of Hydra.
Andrea P. Murillo-Rincon,Alexander Klimovich,Eileen Pemöller,Jan Taubenheim,Benedikt M Mortzfeld,René Augustin,Thomas C. G. Bosch +6 more
TL;DR: The findings indicate that the influence of bacteria on spontaneous contractile activity is present in the early-branching cnidarian hydra as well as in Bilateria, and thus suggest an evolutionary ancient origin of interaction between bacteria and metazoans.
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Prototypical pacemaker neurons interact with the resident microbiota.
Alexander Klimovich,Stefania Giacomello,Stefania Giacomello,Åsa K. Björklund,Louis Faure,Marketa Kaucka,Marketa Kaucka,Christoph Giez,Andrea P. Murillo-Rincon,Ann-Sophie Matt,Doris Willoweit-Ohl,Gabriele Crupi,Jaime de Anda,Gerard C. L. Wong,Mauro D'Amato,Igor Adameyko,Thomas C. G. Bosch +16 more
TL;DR: This study identifies and functionally characterized prototypical ANO/SCN/TRPM ion channel-expressing pacemaker cells in the basal metazoan Hydra and finds that these prototypical pacemaker neurons express a rich set of immune-related genes mediating their interaction with the microbial environment.
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How do environmental factors influence life cycles and development? An experimental framework for early-diverging metazoans
Thomas C. G. Bosch,Maja Adamska,René Augustin,Tomislav Domazet-Lošo,Sylvain Forêt,Sebastian Fraune,Noriko Funayama,Juris A. Grasis,Juris A. Grasis,Mayuko Hamada,Mayuko Hamada,Masayuki Hatta,Bert Hobmayer,Kotoe Kawai,Alexander Klimovich,Michaël Manuel,Chuya Shinzato,Uli Technau,Seungshic Yum,David J. Miller +19 more
TL;DR: Major questions at the interface between animal evolution and development are identified and a road map for research aimed at identifying the mechanisms that link environmental factors to developmental mechanisms in early diverging metazoans is outlined.